The film's lead actor and producer, Ryan Reynolds, announced the news on Twitter by posting a photo of Beetz' name spelled out with dominoes.
Marvel character Domino - real name Neena Thurman - bears the power of telekinesis and is part of mercenary groups known as Six Pack and X-Force.
Her partner is the villain Cable whose appearance in the sequel was teased in Deadpool's post-credits scene. His casting is rumoured to have been one of the reasons why original director Tim Miller abandoned the project making way for John Wick co-director David Leitch.
Beetz plays Van in the Golden Globe-winning comedy series Atlanta opposite Donald Glover. She is said to have beat out the likes of Mackenzie Davis and Scandal star Kerry Washington.Reuse content