The British actor, 25, stars as clean-cut young man Ig Perrish who is accused of raping and murdering his girlfriend Merrin, played by Juno Temple.
Ig has horns growing on his head that hint at what might be his devilish nature and provoke those around him to spill their darkest secrets.
But while the concept seemed promising, reviews have been far less positive, with The Independent describing Horns as "sprawling and wildly uneven" despite Radcliffe's own “strong performance”.
Alexandre Aja's film earned just two stars from many publications, including Rolling Stone, who describes the black comedy as "narratively weak" and "cheap".
The Mirror brands Horns a "dreary low-budget affair" that is "less spine chilling and more eyebrow drooping" while the New York Observer's harsh critique calls it "laughably nonsensical", "borderline unwatchable" and pronounces Ig as Radcliffe's "worst role yet".
The New York Times has been kinder, admiring Aja's "lurid, hysterical visual sensibility" but wishing it was "employed in a more coherent movie", while The Wrap is unusual in praising the "potent chemistry" between the lead stars and insists that the cast strikes "just the right tone".
Another good review comes, surprisingly, from The Hollywood Reporter, who commends "generally excellent effects" and Radcliffe's ability to "take to this vengeful-demon stuff with relish".
Harry Potter stars then and now
Harry Potter stars then and now
1/8 Daniel Radcliffe
The transformation of Daniel Radcliffe from the small boy pictured (right) at the first Harry Potter premiere has grown up into a critically acclaimed actor, seen earlier this year walking the red carpet.
2/8 Emma Watson
Emma Watson, seen (right) at the very first Harry Potter premiere, has gone from acting strength to strength, despite declaring at one point she would be quitting acting to pursue other projects.
3/8 Rupert Grint
Rupert Grint, who plays Ron Weasley in the films, pictured at the very first premiere (aged 13) and earlier this year.
4/8 Matthew Lewis
Possibly the biggest transformation is Matthew Lewis, who played Neville Longbottom in the films. Pictured (right) at the premiere of the Goblet of Fire and (left) earlier this year.
5/8 Tom Felton
Harry's on-screen tormentor Draco Malfoy, played by Tom Felton, who commented that after finishing Harry Potter he was looking forward to playing a less spiteful character.
6/8 Robert Pattinson
Robert Pattinson only appeared in one of the Harry Potter films, despite this it helped to launch him as a globally recognised actor today. Pictured (left) at the premiere of Goblet of Fire and (right) earlier this year at an Australian ceremony
7/8 Bonnie Wright
Harry's on-screen long-term love interest Ginny Weasley was played by Bonnie Wright, pictured (right) at the Prisoners of Azkaban premiere and earlier this year.
8/8 James and Oliver Phelps
James and Oliver Phelps played the wise-cracking Weasley twins and the two were picture together again earlier this year.
Digital Spy, however, thinks Horns is a "misjudged horror", The Guardian bemoans Radcliffe's "devilishly dull" portrayal despite a "few laughs and sharp moments" and The Telegraph concludes that the film "lacks any real bite".
But tonight is both Halloween, and a Friday, making the chances of Horns under-performing at the box office slim. Perhaps swapping Harry Potter for some horns will prove a wise choice from Radcliffe after all.Reuse content