The 25-year-old electronic artist prepared to perform on stage as a nominee at the event, when Laverne mistakenly said the name of the "Your Beautiful" singer-songwriter, to the amusement of the crowd.
Blake later went on to win the sought-after Album of the Year Award and £20,000 prize money at the event hosted at the Roundhouse, London.
In a break between performances and the announcement of the winner, Laverne tweeted:
“Never felt better than I do tonight about artists who have fractionally dissimilar fore and surnames. #MercuryPrize #Irony.”
When asked about the mistake by the BBC, Blake said: “That's happened quite a few times. But you know what? To Lauren I say: 'Don't worry about it, you're amazing'. I certainly don't care.”
In his short speech upon receiving the award he thanked his parents “for showing me the importance of being self-sufficient".
Previous winners of the prize include Antony & The Johnsons, Roni Size, and M People, who clinched the prize from Blur in 1994.
The Mercury Prize is decided by a judging panel of industry experts. This year, the shortlist was chosen from 220 submitted albums from the UK and Ireland.Reuse content