The world's favourite yellow family turns 25 today.
The longest-running US animated series first aired on 17 December 1989, with a Christmas special called "Simpsons Roasting on an Open Fire".
The Matt Groening show has been a hit with fans young and old ever since.
To celebrate, we take a look back at some of the show's most memorable moments, as chosen by our Twitter followers.
1) Spider Pig
"Spider pig, spider pig, does whatever a spider pig does. Can he swing from a web? No he can't he's a pig. Look out's he is a spider pig!"
2) Planet of the Apes: The Musical
"He can talk! He can talk he can talk he can talk he can talk he can talk! I can siiiiiiiiiing!"
3) Mr Burns starves Springfield of electricity
Featuring some of the best dance moves ever seen on the show.
4) When Homer met God
"God I gotta ask you something - what's the meaning of life?"
5) The entirety of the Streetcar Named Marge episode
Whatever would Tennessee Williams make of this.
6) Homer reacts to Lisa's perpetual motion machine
"In this house we obey the laws of thermodynamics!"
7) Ned Flanders plays the devil
"Homer...did you eat that donut?"
8) Homer reacts hilariously to Man Getting Hit By Football
"Football... his groin...it works on so many levels!"
9) Kodos at the Democratic National Convention
"Forward not backward! Always twirling, twirling, twirling towards freedom..."
10) "Happy birthday Lisa"
It's Michael Jackson, singing Lisa Simpson "Happy Birthday" - need we say more?