Compound in red wine shown to mimic benefits of exercise

A compound found in red wine is being touted as "exercise in a bottle" in a new study that looks at the role it plays in animals.

The study, published June 30 in the Federation of American Societies for Experimental Biology Journal , claims that the star ingredient in wine, resveratrol, could slow the negative consequences of a sedentary lifestyle like insulin resistance and loss of bone mineral density.

The new findings seem to confirm the longstanding French paradox: despite a diet high in rich foods like cheese and cream, the French enjoy a low death rate from heart disease.

The researchers were interested in the effects of long-term spaceflight on astronauts, when a zero gravity environment makes it nearly impossible to get adequate exercise. To simulate weightlessness and a sedentary lifestyle in animals, researchers bound their hind legs and tail and fed the rats resveratrol daily.

While the control group showed a decrease in muscle mass and strength, developed insulin resistance and a loss of bone mineral density, the group that received a dose of resveratrol showed none of the complications, the study said.

"There are overwhelming data showing that the human body needs physical activity, but for some of us, getting that activity isn't easy," said Gerald Weissmann, editor-in-chief of the journal.

"A low gravity environment makes it nearly impossible for astronauts. For the earthbound, barriers to physical activity are equally challenging, whether they be disease, injury, or a desk job. Resveratrol may not be a substitute for exercise, but it could slow deterioration until someone can get moving again."

Meanwhile, in another lab study out of Germany, researchers found that the same compound, resveratrol, inhibited pre-fat cells in humans from increasing and converting into mature fat cells. It also hindered the storage of fat.

They also found that resveratrol reduced the production of certain cytokines - cell-signaling protein molecules - that may be linked to the development of obesity-related disorders like diabetes and clogged coronary arteries.

One glass of red wine contains about 1 mg of resveratrol.  Supplements contain 15 to 500 mg per capsule. Currently, there is no consensus on the safe and effective daily dosage of resveratrol.  Supplements are to be avoided by pregnant or breastfeeding women.

The Mayo Clinic defines moderate drinking as two glasses of wine a day for men and one glass a day for women.

Simply eating red grapes with the skin on has been suggested as one way to get resveratrol without consuming alcohol. Other foods that contain resveratrol include peanuts, blueberries and cranberries.

Consult your doctor to determine if supplements are right for you.

http://www.fasebj.org/content/early/2011/06/29/fj.10-177295

Life and Style
ebookNow available in paperback
ebooks
ebookA delicious collection of 50 meaty main courses
Latest stories from i100
Have you tried new the Independent Digital Edition apps?
SPONSORED FEATURES

ES Rentals

    Independent Dating
    and  

    By clicking 'Search' you
    are agreeing to our
    Terms of Use.

    iJobs Job Widget
    iJobs General

    Recruitment Genius: Sales Executive or Senior Sales Executive - B2B Exhibitions

    £18000 - £30000 per annum: Recruitment Genius: A Sales Executive or Senior Sal...

    Recruitment Genius: Head of Support Services

    £40000 - £55000 per annum: Recruitment Genius: This is an exciting opportunity...

    Recruitment Genius: Warehouse Team Leader

    £22000 per annum: Recruitment Genius: This industry leading company produces h...

    Recruitment Genius: Business Development Manager / Sales - OTE £40,000

    £20000 - £40000 per annum: Recruitment Genius: This IT provider for the educat...

    Day In a Page

    The Silk Roads that trace civilisation: Long before the West rose to power, Asian pathways were connecting peoples and places

    The Silk Roads that trace civilisation

    Long before the West rose to power, Asian pathways were connecting peoples and places
    House of Lords: Outcry as donors, fixers and MPs caught up in expenses scandal are ennobled

    The honours that shame Britain

    Outcry as donors, fixers and MPs caught up in expenses scandal are ennobled
    When it comes to street harassment, we need to talk about race

    'When it comes to street harassment, we need to talk about race'

    Why are black men living the stereotypes and why are we letting them get away with it?
    International Tap Festival: Forget Fred Astaire and Ginger Rogers - this dancing is improvised, spontaneous and rhythmic

    International Tap Festival comes to the UK

    Forget Fred Astaire and Ginger Rogers - this dancing is improvised, spontaneous and rhythmic
    War with Isis: Is Turkey's buffer zone in Syria a matter of self-defence – or just anti-Kurd?

    Turkey's buffer zone in Syria: self-defence – or just anti-Kurd?

    Ankara accused of exacerbating racial division by allowing Turkmen minority to cross the border
    Doris Lessing: Acclaimed novelist was kept under MI5 observation for 18 years, newly released papers show

    'A subversive brothel keeper and Communist'

    Acclaimed novelist Doris Lessing was kept under MI5 observation for 18 years, newly released papers show
    Big Blue Live: BBC's Springwatch offshoot swaps back gardens for California's Monterey Bay

    BBC heads to the Californian coast

    The Big Blue Live crew is preparing for the first of three episodes on Sunday night, filming from boats, planes and an aquarium studio
    Austin Bidwell: The Victorian fraudster who shook the Bank of England with the most daring forgery the world had known

    Victorian fraudster who shook the Bank of England

    Conman Austin Bidwell. was a heartless cad who carried out the most daring forgery the world had known
    Car hacking scandal: Security designed to stop thieves hot-wiring almost every modern motor has been cracked

    Car hacking scandal

    Security designed to stop thieves hot-wiring almost every modern motor has been cracked
    10 best placemats

    Take your seat: 10 best placemats

    Protect your table and dine in style with a bold new accessory
    Ashes 2015: Alastair Cook not the only one to be caught in The Oval mindwarp

    Cook not the only one to be caught in The Oval mindwarp

    Aussie skipper Michael Clarke was lured into believing that what we witnessed at Edgbaston and Trent Bridge would continue in London, says Kevin Garside
    Can Rafael Benitez get the best out of Gareth Bale at Real Madrid?

    Can Benitez get the best out of Bale?

    Back at the club he watched as a boy, the pressure is on Benitez to find a winning blend from Real's multiple talents. As La Liga begins, Pete Jenson asks if it will be enough to stop Barcelona
    Athletics World Championships 2015: Beijing witnesses new stage in the Jessica Ennis-Hill and Katarina Johnson-Thompson heptathlon rivalry

    Beijing witnesses new stage in the Jess and Kat rivalry

    The last time the two British heptathletes competed, Ennis-Hill was on the way to Olympic gold and Johnson-Thompson was just a promising teenager. But a lot has happened in the following three years
    Jeremy Corbyn: Joining a shrewd operator desperate for power as he visits the North East

    Jeremy Corbyn interview: A shrewd operator desperate for power

    His radical anti-austerity agenda has caught the imagination of the left and politically disaffected and set a staid Labour leadership election alight
    Isis executes Palmyra antiquities chief: Defender of ancient city's past was killed for protecting its future

    Isis executes Palmyra antiquities chief

    Robert Fisk on the defender of the ancient city's past who was killed for protecting its future