Asthma inhaler may fail for child sufferers
Wednesday 07 October 2009
The most widely used asthma inhaler in Britain may fail to prevent attacks in one in 10 children who use them, a study has shown.
About 100,000 children – 13 per cent of those with asthma – carry a gene mutation that means the common "blue" inhaler containing salbutamol (brand name Ventolin) may not protect them. Researchers from the University of Dundee, and Brighton and Sussex Medical School, found that children with the mutation who used their inhaler daily had a 30 per cent increased risk of asthma attacks compared with those who had a normal form of the gene. The findings are published in the Journal of Allergy and Clinical Immunology.
Experts warned parents and children not to panic and to continue to use their inhaler as prescribed. They said the research needed confirmation by further studies.
Co-author Professor Somnath Mukhopadhyay, of the Brighton and Sussex Medical School, said: "Salbutamol via the blue inhaler is effective reliever treatment in most children, but it is common experience among doctors that a proportion of children do not seem to respond to this medicine as well as others.
"The reason for this appears to be a genetic variant called Arg16. Although this gene does not increase an individual's chance of getting asthma in the first place or make their asthma worse, it does seem to alter how well certain asthma medicines will work."
Life & Style blogs
The mother who never gave up on her child abused by the Oxford child sex ring
Britain scrapes into top 25 countries in the world to be a mother in Save the Children report
What do the emoji on Snapchat mean?
The 12 most sexually satisfied countries in the world revealed
Uploading pictures to find out how old you are gives Microsoft the right to post them wherever they want
- 2 Italian police 'reveal' what Jesus looked like as a young boy
- 3 General Election 2015: 14-year-old boy asks Nick Clegg – 'can you kill Katie Hopkins?'
- 4 University student in court for allegedly covering housemates' food in window cleaner and spit
- 5 Ryan Gosling posts tribute to 'Ryan Gosling Won't Eat His Cereal' creator Ryan McHenry
£13676.46 - £16411.61 per annum + OTE: SThree: SThree Trainee Recruitment Cons...
£18000 - £22000 per annum + training: Ashdown Group: Business and Marketing Gr...
£20000 - £25000 per annum + Commission: SThree: Are you great at building rela...
£20000 - £22000 per annum + excellent benefits: Ashdown Group: Application Sup...