Seaweed 'could fight tooth-decay'

 

Microbes found on seaweed could provide an unexpected weapon in the fight against tooth decay, scientists have said.

They used an enzyme isolated from the marine bacterium Bacillus licheniformis which they were originally researching for cleaning ships' hulls.

Instead, the Newcastle University team will tell the Society for Applied Microbiology Summer Conference that it could have a range of medical applications, including teeth cleaning.

While toothpastes are effective, there are still hard-to-reach areas between teeth where the bacteria in plaque can erode enamel, causing cavities.

Dr Nicholas Jakubovics of Newcastle University's School of Dental Sciences believes better products offering more effective treatment can be made using the enzyme.

He said: "Plaque on your teeth is made up of bacteria which join together to colonise an area in a bid to push out any potential competitors.

"Traditional toothpastes work by scrubbing off the plaque containing the bacteria - but that's not always effective - which is why people who religiously clean their teeth can still develop cavities.

"Work in a test tube has shown that this enzyme can cut through the plaque or layer of bacteria and we want to harness this power into a paste, mouthwash or denture cleaning solution."

When threatened, bacteria shield themselves in a slimy protective barrier known as a biofilm.

It is made up of bacteria held together by a web of extracellular DNA which binds the bacteria to each other and to a solid surface - in this case in the plaque around the teeth and gums.

The biofilm protects the bacteria from attack by brushing, chemicals or even antibiotics.

But after studying Bacillus licheniformis, which is found on the surface of seaweed, Newcastle University scientists found that when the bacteria want to move on, they release an enzyme which breaks down the external DNA. That breaks up the biofilm and releases the bacteria from the web.

Professor Burgess, who led the research, said: "It's an amazing phenomenon. The enzyme breaks up and removes the bacteria present in plaque and importantly, it can prevent the build up of plaque too.

"When I initially began researching how to break down these layers of bacteria, I was interested in how we could keep the hulls of ships clear but we soon realised that the mechanism we had discovered had much wider uses.

"If we can contain it within a toothpaste we would be creating a product which could prevent tooth decay.

"This is just one of the uses we are developing for the enzyme as it has huge potential such as in helping keep clean medical implants such as artificial hips and speech valves which also suffer from biofilm infection."

The team will now look to collaborate with industry to carry out more tests and product development.

PA

Arts and Entertainment
Joe Cocker performing on the Stravinski hall stage during the Montreux Jazz Festival, in Montreux, Switzerland in 2002
musicHe 'turned my song into an anthem', says former Beatle
News
Clarke Carlisle
sport
Sport
footballStoke City vs Chelsea match report
Arts and Entertainment
theatreThe US stars who've taken to UK panto, from Hasselhoff to Hall
PROMOTED VIDEO
Life and Style
ebookNow available in paperback
Life and Style
ebooksA superb mix of recipes serving up the freshest of local produce in a delicious range of styles
Life and Style
Approaching sale shopping in a smart way means that you’ll get the most out of your money
life + styleSales shopping tips and tricks from the experts
News
newsIt was due to be auctioned off for charity
News
Coca-Cola has become one of the largest companies in the world to push staff towards switching off their voicemails, in a move intended to streamline operations and boost productivity
peopleCoca-Cola staff urged to switch it off to boost productivity
Environment
Sir David Attenborough
environment... as well as a plant and a spider
Voices
'That's the legal bit done. Now on to the ceremony!'
voicesThe fight for marriage equality isn't over yet, says Siobhan Fenton
Latest stories from i100
Have you tried new the Independent Digital Edition apps?

ES Rentals

    Independent Dating
    and  

    By clicking 'Search' you
    are agreeing to our
    Terms of Use.

    iJobs Job Widget
    iJobs General

    Austen Lloyd: Regulatory / Compliance / Exeter

    Excellent Salary: Austen Lloyd: Exeter - An excellent opportunity for a Solici...

    Ashdown Group: IT Support Technician - 12 Month Fixed Term - Shrewsbury

    £17000 - £20000 per annum: Ashdown Group: IT Helpdesk Support Technician - 12 ...

    The Jenrick Group: Maintenance Planner

    £28000 - £32000 per annum + pension + holidays: The Jenrick Group: Maintenance...

    The Jenrick Group: World Wide PLC Service Engineer

    £30000 - £38000 per annum + pesion + holidays: The Jenrick Group: World Wide S...

    Day In a Page

    Isis in Iraq: Yazidi girls killing themselves to escape rape and imprisonment by militants

    'Jilan killed herself in the bathroom. She cut her wrists and hanged herself'

    Yazidi girls killing themselves to escape rape and imprisonment
    Ed Balls interview: 'If I think about the deficit when I'm playing the piano, it all goes wrong'

    Ed Balls interview

    'If I think about the deficit when I'm playing the piano, it all goes wrong'
    He's behind you, dude!

    US stars in UK panto

    From David Hasselhoff to Jerry Hall
    Grace Dent's Christmas Quiz: What are you – a festive curmudgeon or top of the tree?

    Grace Dent's Christmas Quiz

    What are you – a festive curmudgeon or top of the tree?
    Nasa planning to build cloud cities in airships above Venus

    Nasa planning to build cloud cities in airships above Venus

    Planet’s surface is inhospitable to humans but 30 miles above it is almost perfect
    Surrounded by high-rise flats is a little house filled with Lebanon’s history - clocks, rifles, frogmen’s uniforms and colonial helmets

    Clocks, rifles, swords, frogmen’s uniforms

    Surrounded by high-rise flats is a little house filled with Lebanon’s history
    Return to Gaza: Four months on, the wounds left by Israel's bombardment have not yet healed

    Four months after the bombardment, Gaza’s wounds are yet to heal

    Kim Sengupta is reunited with a man whose plight mirrors the suffering of the Palestinian people
    Gastric surgery: Is it really the answer to the UK's obesity epidemic?

    Is gastric surgery really the answer to the UK's obesity epidemic?

    Critics argue that it’s crazy to operate on healthy people just to stop them eating
    Homeless Veterans appeal: Christmas charity auction Part 2 - now LIVE

    Homeless Veterans appeal: Christmas charity auction

    Bid on original art, or trips of a lifetime to Africa or the 'Corrie' set, and help Homeless Veterans
    Pantomime rings the changes to welcome autistic theatre-goers

    Autism-friendly theatre

    Pantomime leads the pack in quest to welcome all
    The week Hollywood got scared and had to grow up a bit

    The week Hollywood got scared and had to grow up a bit

    Sony suffered a chorus of disapproval after it withdrew 'The Interview', but it's not too late for it to take a stand, says Joan Smith
    From Widow Twankey to Mother Goose, how do the men who play panto dames get themselves ready for the performance of a lifetime?

    Panto dames: before and after

    From Widow Twankey to Mother Goose, how do the men who play panto dames get themselves ready for the performance of a lifetime?
    Thirties murder mystery novel is surprise runaway Christmas hit

    Thirties murder mystery novel is surprise runaway Christmas hit

    Booksellers say readers are turning away from dark modern thrillers and back to the golden age of crime writing
    Anne-Marie Huby: 'Charities deserve the best,' says founder of JustGiving

    Anne-Marie Huby: 'Charities deserve the best'

    Ten million of us have used the JustGiving website to donate to good causes. Its co-founder says that being dynamic is as important as being kind
    The botanist who hunts for giant trees at Kew Gardens

    The man who hunts giants

    A Kew Gardens botanist has found 25 new large tree species - and he's sure there are more out there