Test 'could spare women chemotherapy'
Friday 16 December 2011
Almost half of women with the most common form of early breast cancer could be spared chemotherapy thanks to a genetic test, research suggests.
The Oncotype DX test involves the examination of genes taken from a sample of a tumour removed during surgery.
It can help doctors decide whether chemotherapy would actually benefit patients and the risk of cancer returning.
Research carried out by Simon Holt, a breast surgeon at the Hywel Dda Health Board in Wales, found that 46% of patients with early stage disease could be spared unnecessary chemotherapy.
The 142 NHS patients in his study had oestrogen receptor positive breast cancer, the most common type, and had initially been offered chemotherapy and hormone therapy.
The Oncotype DX test is currently being reviewed by the National Institute for Health and Clinical Excellence (Nice) for widespread use on the NHS.
Mr Holt said: "With nearly 50,000 women diagnosed with early stage breast cancer each year in the UK, a genomic test like Oncotype DX that is capable of predicting treatment benefits and/or outcomes may have an important role to play in improving treatment decision making and ultimately impacting on quality of care.
"Oncotype DX allows us to use our health funds more effectively while sparing patients from unnecessary chemotherapy."
Mr Holt presented his findings at the San Antonio Breast Cancer Symposium last week.
Life & Style blogs
10 ways we damage our teeth – without realising
Facebook Messenger sends 'creepily' precise location data, as revealed by Marauders Map Chrome extension
What do the emoji on Snapchat mean?
iPhone 'effective power' text: how to be safe from iOS bug that lets people crash your phone
Video claims California will be hit by huge earthquake because of the alignment of the planets — but it’s probably wrong
- 1 10 ways we damage our teeth – without realising
- 2 Fifa corruption arrests: Nike reported to be 'multinational sportswear company' at centre of bribery claims over Brazil shirt deal
- 3 Facebook Messenger sends 'creepily' precise location data, as revealed by Marauders Map Chrome extension
- 4 Bahar Mustafa: Goldsmiths Students' Union diversity officer to keep her job after vote of no confidence petition fails
- 5 Photo of wedding guest proposing to girlfriend in front of bride and groom goes viral
Negotiable: Recruitment Genius: A Digital Web Designer is required to join a f...
Negotiable: Recruitment Genius: This is a fantastic opportunity to develop an ...
Negotiable: Recruitment Genius: One of the South East's fastest growing full s...
£35-40k (DOE) + Benefits: Guru Careers: We are seeking a Marketing Communicati...