Infants with autistic siblings at higher risk: US study
Tuesday 16 August 2011
Infants have higher risk of developing autism if they have siblings with the disorder, a US study found Monday.
The risk that an infant with an older sibling with autism also will develop the disorder, previously estimated at 3-10 percent, is 19 percent, according to the study by researchers at the University of California Davis.
For male infants the risk was even higher, at 26 percent, and for infants with more than one older sibling with autism the risk of recurrence jumped to 32 percent, according to the study.
Autism, a complex disorder that affects a child's ability to think, learn, communicate and interact socially, occurs in one out of 110 children born in the United States, according to the US Center for Disease Control (CDC).
Males account for 80 percent of diagnosed cases, researchers said.
"This is the largest study of the siblings of children with autism ever conducted," said Sally Ozonoff, professor of psychiatry and behavioral sciences at UC Davis's MIND Institute and the study's lead author.
"There is no previous study that identified a risk of recurrence that is this high."
The study involved 664 infants whose average age was eight months, with two-thirds recruited younger than six months. The researchers followed their development until 36 months, when they were tested for autism.
Of the 664 infants, 132 met the criteria for an "autism spectrum disorder," with 54 diagnosed with autistic disorder and 78 diagnosed with a milder form of the disease.
The study found that in families with one older child with autism the rate of recurrence was 20.1 percent. Only 37 infants had more than one sibling with autism, but for them the recurrence rate was 32.2 percent.
The study was published online Monday and will appear in print in the September issue of the journal "Pediatrics," the researchers said.
Life & Style blogs
Dating site hack reveals sexual secrets of 4 million users
Well, it seemed like a good idea at the time: 10 worst gadgets of recent times
Crystal meth addict 'gouged out his eyes and ate them' while high on drug, Australian MP claims
What do the emoji on Snapchat mean?
Teenager tries to buy elderly homeless man breakfast at McDonald's but is told homeless people cannot be served under 'new policy'
- 1 Crystal meth addict 'gouged out his eyes and ate them' while high on drug, Australian MP claims
- 2 Saudi Arabia 'seeking to head United Nations Human Rights Council'
- 3 Irish people are travelling home from all over the world so they can vote to legalise gay marriage
- 4 Witch doctor arrested after forcing newborn baby to walk in Indian village
- 5 Arsenal fan asks the Queen for tickets to the FA Cup final - gets a reply from Buckingham Palace
£40-50K: Guru Careers: We are seeking an experienced Software / C# Developer w...
£35 - 40k + Benefits: Guru Careers: We are seeking a Software Developer (JavaS...
£18000 - £23000 per annum + Commission: SThree: As a Trainee Recruitment Consu...