Pregnancy ups HIV risk in negative partner

Research presented at the M2010, the 6th biennial International Microbicides Conference in Pittsburgh, on May 23 detailed a novel study that has found HIV transmission from a pregnant positive partner increases two-fold in HIV negative men.


 

For decades public health professionals and researchers have been battling HIV and studying the links between mother-to-child transmission (MTCT) and ways to empower females to practice safe sex due to the prevalence of male-to-female transmission.

Strides have been made but the rate of treatment is dwarfed by transmission, 2:5 according to Microbicide Trial Network's (MTN) analysis of 2007 data from UNAIDS and the US Center for Disease Control (CDC). "In sub-Saharan Africa women aged 15-24 are the highest risk group Globally, women account for half of all HIV infections, and in sub-Saharan Africa, women comprise 60 percent of all infected adults," and in "southern Africa women aged 15 to 24 are at least three times more likely than their male peers to be infected with HIV."

According to Nelly Mugo, MD, MPH, a research scientist at the University of Washington, University of Nairobi/ Kenyatta National Hospital (KNH) and East African director of the Partners in Prevention HSV/HIV Transmission Study, Pre-Exposure Prophylaxis (PrEP), pregnant female-to-male transmission is something that needs greater attention as "biological changes that occur during pregnancy may make women more infectious than they would be otherwise."

The research took place in Botswana, Kenya, Rwanda, South Africa, Tanzania, Uganda and Zambia where 3,321 couples (1,085 couples included a positive male and 2,236 couples where the female was positive) were monitored for two years producing 823 pregnancies.

The study concluded "pregnancy was associated with increased risk of both female-to-male and male-to-female HIV transmission" and "...the link between pregnancy and HIV risk was much clearer (in men), even after considering whether or not they had engaged in unprotected sex or were circumcised. Measures of viral load and CD4 counts of the infected partner also had no bearing." 

The authors cautioned that much more researcher is needed and noted, "for women with an HIV- infected partner, the study found that factors other than pregnancy also likely contributed to this increased risk, such as sexual behavior."

Nonetheless, "increased female-to-male transmission of HIV during pregnancy may be due to physiological and immunological changes that occur with pregnancy."

For more information on M2010, go to: http://www.microbicides2010.org

Life and Style
ebookNow available in paperback
ebooks
ebookPart of The Independent’s new eBook series The Great Composers
  • Get to the point
Latest stories from i100
Have you tried new the Independent Digital Edition apps?

ES Rentals

    Independent Dating
    and  

    By clicking 'Search' you
    are agreeing to our
    Terms of Use.

    iJobs Job Widget
    iJobs General

    Guru Careers: Software Engineer / Software Developer

    £40-50K: Guru Careers: We are seeking an experienced Software Engineer / Softw...

    Ashdown Group: Trainee Consultant - Surrey/ South West London

    £22000 per annum + pension,bonus,career progression: Ashdown Group: An establi...

    Ashdown Group: Trainee Consultant - Surrey / South West London

    £22000 per annum + pension,bonus,career progression: Ashdown Group: An establi...

    Ashdown Group: Recruitment Consultant / Account Manager - Surrey / SW London

    £40000 per annum + realistic targets: Ashdown Group: A thriving recruitment co...

    Day In a Page

    Fishing for votes with Nigel Farage: The Ukip leader shows how he can work an audience as he casts his line to the disaffected of Grimsby

    Fishing is on Nigel Farage's mind

    Ukip leader casts a line to the disaffected
    Who is bombing whom in the Middle East? It's amazing they don't all hit each other

    Who is bombing whom in the Middle East?

    Robert Fisk untangles the countries and factions
    China's influence on fashion: At the top of the game both creatively and commercially

    China's influence on fashion

    At the top of the game both creatively and commercially
    Lord O’Donnell: Former cabinet secretary on the election and life away from the levers of power

    The man known as GOD has a reputation for getting the job done

    Lord O'Donnell's three principles of rule
    Rainbow shades: It's all bright on the night

    Rainbow shades

    It's all bright on the night
    'It was first time I had ever tasted chocolate. I kept a piece, and when Amsterdam was liberated, I gave it to the first Allied soldier I saw'

    Bread from heaven

    Dutch survivors thank RAF for World War II drop that saved millions
    Britain will be 'run for the wealthy and powerful' if Tories retain power - Labour

    How 'the Axe' helped Labour

    UK will be 'run for the wealthy and powerful' if Tories retain power
    Rare and exclusive video shows the horrific price paid by activists for challenging the rule of jihadist extremists in Syria

    The price to be paid for challenging the rule of extremists

    A revolution now 'consuming its own children'
    Welcome to the world of Megagames

    Welcome to the world of Megagames

    300 players take part in Watch the Skies! board game in London
    'Nymphomaniac' actress reveals what it was really like to star in one of the most explicit films ever

    Charlotte Gainsbourg on 'Nymphomaniac'

    Starring in one of the most explicit films ever
    Robert Fisk in Abu Dhabi: The Emirates' out-of-sight migrant workers helping to build the dream projects of its rulers

    Robert Fisk in Abu Dhabi

    The Emirates' out-of-sight migrant workers helping to build the dream projects of its rulers
    Vince Cable interview: Charging fees for employment tribunals was 'a very bad move'

    Vince Cable exclusive interview

    Charging fees for employment tribunals was 'a very bad move'
    Iwan Rheon interview: Game of Thrones star returns to his Welsh roots to record debut album

    Iwan Rheon is returning to his Welsh roots

    Rheon is best known for his role as the Bastard of Bolton. It's gruelling playing a sadistic torturer, he tells Craig McLean, but it hasn't stopped him recording an album of Welsh psychedelia
    Morne Hardenberg interview: Cameraman for BBC's upcoming show Shark on filming the ocean's most dangerous predator

    It's time for my close-up

    Meet the man who films great whites for a living
    Increasing numbers of homeless people in America keep their mobile phones on the streets

    Homeless people keep mobile phones

    A homeless person with a smartphone is a common sight in the US. And that's creating a network where the 'hobo' community can share information - and fight stigma - like never before