Bronchitis pill results `better than expected'

Sufferers of chronic bronchitis were offered hope yesterday after Cortecs, the UK healthcare company specialising in oral drug delivery, said results from trials of a bronchitis vaccine pill were much better than expected. Cortecs' share price, which has been under a cloud since May, surged almost 10 per cent to 237.5p.

Glen Travers, Cortecs chief executive, said patients taking the pill, called Pseudostat, in phase II trials had 10 times fewer bouts of infection than those on dummy pills in the five months after treatment ended. "Pseudostat is quite impressive. We have a unique product that can deal with a respiratory disease that hasn't been adequately treated with other medicines," Mr Travers said.

Analysts were cautiously optimistic. Stewart Adkins of Lehman Brothers said: "These results look very positive. The key is whether people on this drug need to use less antibiotic. But if these results indicate that Cortecs' oral vaccine technology works, it could be quite significant."

Mr Travers said the company would begin final-stage clinical trials of Pseudostat this year and would file for registration in Europe in 1998. "That is aggressive, but we really plan to push this drug," he said.

Chronic bronchitis, a bacterial lung infection responsible for 5 per cent of all deaths in the UK, is treated with antibiotics and often involves hospitalisation. Mr Travers said patients taking Pseudostat needed to take less antibiotic and of the 91 sufferers tested, none taking Pseudostat needed to be hospitalised.

Commenting on the recent share price weakness, which followed Cortecs' presentation in May of crucial final-stage data on its lead pill to treat brittle bones, Macritonin, Mr Travers said: "We don't feel any nervousness about that trial."

Start your day with The Independent, sign up for daily news emails
News
ebooksAn unforgettable anthology of contemporary reportage
Latest stories from i100
Have you tried new the Independent Digital Edition apps?
Independent Dating
and  

By clicking 'Search' you
are agreeing to our
Terms of Use.

iJobs Job Widget
iJobs Money & Business

Recruitment Genius: Digital Optimisation Executive - Marketing

£30000 - £35000 per annum: Recruitment Genius: The UK's fastest growing, multi...

Recruitment Genius: Financial Reporting Manager

£70000 - £90000 per annum: Recruitment Genius: A Financial Reporting Manager i...

Recruitment Genius: Payments Operations Assistant

£23000 - £25000 per annum: Recruitment Genius: They win lots of awards for the...

Recruitment Genius: Telephone Debt Negotiator

£13500 - £20000 per annum: Recruitment Genius: This nationwide enforcement com...

Day In a Page

On your feet! Spending at least two hours a day standing reduces the risk of heart attacks, cancer and diabetes, according to new research

On your feet!

Spending half the day standing 'reduces risk of heart attacks and cancer'
Liverpool close in on Milner signing

Liverpool close in on Milner signing

Reds baulk at Christian Benteke £32.5m release clause
With scores of surgeries closing, what hope is there for the David Cameron's promise of 5,000 more GPs and a 24/7 NHS?

The big NHS question

Why are there so few new GPs when so many want to study medicine?
Big knickers are back: Thongs ain't what they used to be

Thongs ain't what they used to be

Big knickers are back
Thurston Moore interview

Thurston Moore interview

On living in London, Sonic Youth and musical memoirs
In full bloom

In full bloom

Floral print womenswear
From leading man to Elephant Man, Bradley Cooper is terrific

From leading man to Elephant Man

Bradley Cooper is terrific
In this the person to restore our trust in the banks?

In this the person to restore our trust in the banks?

Dame Colette Bowe - interview
When do the creative juices dry up?

When do the creative juices dry up?

David Lodge thinks he knows
The 'Cher moment' happening across fashion just now

Fashion's Cher moment

Ageing beauty will always be more classy than all that booty
Thousands of teenage girls enduring debilitating illnesses after routine school cancer vaccination

Health fears over school cancer jab

Shock new Freedom of Information figures show how thousands of girls have suffered serious symptoms after routine HPV injection
Fifa President Sepp Blatter warns his opponents: 'I forgive everyone, but I don't forget'

'I forgive everyone, but I don't forget'

Fifa president Sepp Blatter issues defiant warning to opponents
Extreme summer temperatures will soon cause deaths of up to 1,700 more Britons a year, says government report

Weather warning

Extreme summer temperatures will soon cause deaths of up to 1,700 more Britons a year, says government report
LSD: Speaking to volunteer users of the drug as trials get underway to see if it cures depression and addiction

High hopes for LSD

Meet the volunteer users helping to see if it cures depression and addiction
German soldier who died fighting for UK in Battle of Waterloo should be removed from museum display and given dignified funeral, say historians

Saving Private Brandt

A Belgian museum's display of the skeleton of a soldier killed at Waterloo prompts calls for him to be given a dignified funeral