The 52-year-old GP from Hyde, Greater Manchester, appeared before magistrates in Ashton-under-Lyne charged with murdering Jean Lilley, 59, and Irene Turner, 67.
The bodies of the two women were exhumed last month for post-mortem examinations.
Mrs Lilley died at her home in Hyde on 25 April last year and Mrs Turner at her home on 11 July 1996.
Dr Shipman, of Tameside, who runs a one-man practice in Hyde, was remanded in custody until Monday.
The bodies of nine female patients have now been exhumed as part of an investigation by Greater Manchester Police.Reuse content