McColgan won in her debut race two years ago and the 10-kilometre event will probably be her last race before her next target, the Tokyo Marathon, on 30 November.
The 1991 10,000 metres world champion ran a personal best 10-mile time of exactly 52min when winning the Great South Run a fortnight earlier, despite suffering from a virus, which was diagnosed as fluid behind the ear.
Now she is aiming to finish with a victory before she leaves for her training base in Gainesville, Florida, on Thursday.
McColgan said: "After Sunday's race my sights will be firmly set on Tokyo and next year's London Marathon."Reuse content