Around 140 BBC journalists will lose their jobs in the next 12 months as part of a round of cost-cutting measures designed to save the corporation millions of pounds.
They are among 500 job losses across BBC News and the English Regions in the next five years as part of what the corporation calls Delivering Quality First (DQF).
BBC News Director Helen Boaden said the move would "result in the closure of around 140 posts by April next year".
In an email sent to staff today, she said: "I don't pretend that these changes will be easy or painless for individuals or teams. As we have always done, we will work extremely hard to avoid any compulsory redundancies though as the BBC gets smaller, we cannot guarantee complete success in this area."
According to the BBC in-house newspaper Ariel, the job losses will include "Three Newsnight reporters, three Radio 4 News reporters and 17 posts across Radio 1 and 1Xtra news services".
Radio 4 shows Taking a Stand and Beyond Westminster will be cut and a presenter will be axed from the News Channel.
The BBC's DQF blueprint was unveiled last year and includes plans to sell off buildings, show more repeats and shed thousands of jobs by 2016.
It includes savings of £670 million a year by 2016/17 on top of £30 million of savings generated by exceeding targets for its current efficiency programme.
Around 2,000 BBC staff have also moved to Media City in Salford, including people working for Radio 6 Music, the BBC Sport website and part of Radio 5 Live.