Naked images of the former couple are said to have been circulated online.
A spokesperson for Smith and Lowe could not be reached.
The pair are two of over 100 celebrities to have been targeted in the scandal, with others including Jennifer Lawrence, Kim Kardashian, Rihanna, Cara Delevingne, Kirsten Dunst, Winona Ryder, Kate Upton and Ariana Grande. The photographs were first published on online forum 4Chan.
The FBI and Apple are both conducting investigations into the apparent widespread invasion of personal accounts thought to be connected to the iCloud service.
Earlier this week, Nick Hogan became the first male victim to be targeted.
On Tuesday, Lawrence broke her silence on the hacking, branding the incident a "sex crime".
"It is not a scandal. It is a sex crime," Lawrence told Vanity Fair. "It is a sexual violation. It’s disgusting. The law needs to be changed, and we need to change. That’s why these websites are responsible.
"Just the fact that somebody can be sexually exploited and violated, and the first thought that crosses somebody’s mind is to make a profit from it. It’s so beyond me. I just can’t imagine being that detached from humanity. I can’t imagine being that thoughtless and careless and so empty inside."
She also reprimanded anyone who had looked at the pictures.
"You should cower with shame," she continued. "Even people who I know and love say, 'Oh, yeah, I looked at the pictures.' I don’t want to get mad, but at the same time I’m thinking, I didn’t tell you that you could look at my naked body."