The Jewish actress said that the actions of the country, governed by Prime Minister Benjamin Netanyahu, had allowed the world to reignite existing prejudices against Jewish people, whom she claimed people "didn’t like".
"I loathe Hamas, but they were democratically elected and Israel's behaviour is not acceptable," she told the Radio Times. "There's been a troubling backlash.
"I don't think people like Jews," she continued. "They never have. English literature, my great love, is full of greasy and treacherous Jews.
"I'm lucky they like me, and one always needs a Jewish accountant."
Margolyes, whose family are descendants of Jewish immigrants from Belarus, added: "Anti-Semitism is horrible and can't be defended, but Israel is stupid for allowing people to vent it."
The famous on Israel-Gaza
The famous on Israel-Gaza
1/21 Penelope Cruz and Javier Bardem
Oscar-winning married actors Penelope Cruz and Javier Bardem signed an open letter accused Israel of "genocide". They said: "Gaza is living through horror these days, besieged and attacked by land, sea and air'.
2/21 Zayn Malik
The One Direction singer was bombarded with Twitter death threats after posting #FreePalestine to his 13 million followers. The tweet collected over 130,000 retweets, but it soon became apparent that not everyone agreed with his opinion.
3/21 Mia Farrow
Mia Farrow, the actress and Unicef ambassador, said on Twitter: 'We can passionately protest Israel's assault upon Gaza without descending, even remotely, into the hideousness of anti-Semitism'.
4/21 Katy Perry
Way back in 2011, Katy Perry faced a slew of angry responses from Palestinians and their supporters after she tweeted to her fans, asking them to 'Pray for Israel'.
ABC via Getty
5/21 Massive Attack
Massive Attack spoke of their ‘love and commitment’ to supporting the plight of young Palestinian refugees after the band visited the Bourj el-Barajneh refugee camp in Lebanon.
6/21 Selena Gomez
The former Disney child star caused a stir when she posted an image on her Instagram account than began: 'It's about humanity. Pray for Gaza.' Joan Rivers responded to the TMZ celebrity news website: 'Oh, Selena Gomez, yeah, that college grad. Well if Selena said that...let’s see if she can spell Palestinian'.
7/21 Russell Brand
Russell Brand is currently caught up in an entertaining spat with Fox News anchor Sean Hannity. Brand uploaded a video where he accused Hannity of terrorism after his agressive behaviour in an Israel-Gaza debate. Hannity, who is famously right-wing and pro-Israel, asked Yousef Munayyer if he was 'thick in the head'.
Rihanna tweeted, then deleted, the hashtag #FreePalestine after eight minutes. She claimed its publication was an accident.
9/21 John Legend
The singer waded into the debate on Twitter when he wrote: 'So sick watching our Secretary of State have to grovel so hard to tell Israel how much he loves them while Israeli cabinet shits on him'.
10/21 Bar Refaeli
Leonardo DiCaprio's former girlfriend added to the debate when she posted a quote on her Instagram account, which she attributed to Abraham Lincoln. Unfortunately it was actually taken from a Lincoln figure encountered by Captain Kirk and Spock in Star Trek, season three, episode 22.
11/21 Bill Maher
Bill Maher received a storm of criticism after he compared Hamas to a 'crazy woman trying to kill you'. 'You can only hold her wrists for so long before you have to slap her,' he tweeted.
12/21 Jon Voight
The actor and father of Angelina Jolie unleashed a rant on Fox News. Reading from a script, he criticised Obama’s actions over the current unrest in Israel and Gaza.
13/21 Joey Barton
Despite already getting into a dispute with Yossi Benayoun over comments on the Israel-Gaza conflict: Joey Barton has continued to deplore the violence in Gaza, tweeting the hashtag '#stopisraelkillinginnocents'.
14/21 Howard Stern
When a caller attempted to blame Israel for the war with Hamas last week, SiriusXM radio host Howard Stern told him to'“F*** off!' before launching into an impassioned defense of Israel, saying: “If you’re anti-Israel, then you’re anti-America”.
15/21 Wonder Woman
Otherwise known as Gal Gadot: the Israeli actress took to Instagram, writing: 'I am sending my love and prayers to my fellow Israeli citizens. Especially to all the boys and girls who are risking their lives protecting my country against the horrific acts conducted by Hamas, who are hiding like cowards behind women and children'.
16/21 Piers Morgan
Piers Morgan was branded 'Zionest scum' for his stream of tweets about the Israel-Gaza conflict. He declared various opinions such as 'I like Jews. I like Arabs' and 'Same nonsense made Northern Ireland a murderous tinderbox for 30 years'.
17/21 Joan Rivers
Joan Rivers didn't hold back when she was interviewed by TMZ; likening Israel's position to that of New York if it was attacked by New Jersey. Asked where she thought civilians caught up in the crossfire were supposed to go, she replied: 'I don't care, they started'.
18/21 Dwight Howard
NBA star Dwight Howard 'did a Rihanna' - tweeting '#FreePalestine' before quickly deleting it and spending the rest of the day apologizing for the 'mistake'.
19/21 Nicole Kidman and Keith Urban
Nicole Kidman uploaded a short video to her Facebook page, featuring Keith Urban with their daughters Sunday Rose and Faith Margaret, captioned: 'Keith, the girls and I are joining Reba McEntire to #PrayForPeace. xxNic'.
20/21 Simon Cowell
X Factor boss pledged almost £100,000 to the Friends of the Israel Defense Forces at a US fund-raiser in Beverly Hills in 2012. The gala brought in more than £12million for the organisation, which helps to provide welfare services for IDF soldiers and their bereaved families. So far, however, he has only commented on the conflict to say that he is "praying for peace".
21/21 Brian Eno
Musician and producer Brian Eno condemned the Israeli action in Gaza as 'ethnic cleansing' in an open letter on David Byrne's website.
The Israel-Gaza conflict in July and August claimed the lives of 2,100 Palestinians – many of whom were civilians. The death toll starkly contrasted that of Israel, which suffered 70 casualties.
According to the Sunday Times, more than 100 incidents of anti-Semitic violence were recorded by community organisations and police in July during the most heated period of fighting between the two sides.
Four teenagers were charged with racially aggravated common assault after a rabbi was reportedly attacked near a Jewish boarding school in Gateshead on 18 July, while in Belfast, on the same day, bricks were hurled through a synagogue window.
On 12 July, following a pro-Palestine rally, a group of men piled into four or five cars and drove through a Jewish area of Greater Manchester crying "Heil Hitler", while also pelting pedestrians with eggs and drinks cans.
Mark Gardner, Director of Communications at CST, also told The Independent that week-on-week the number of attacks has been increasing, though "what’s particularly important for us is that we’ve not seen the kind of high profile violence that has been occurring in France.
"It’s that kind of high profile violence that causes major panic."
Tensions were strained as pro-Palestine and pro-Israel rallies erupt in cities across Europe, also.
Clashes broke out at a banned pro-Gaza demonstration in Paris the same month, with tear gas deployed by riot police after protesters threw stones and other missiles.
France, which has western Europe’s largest Muslims and Jewish populations, had been forced, at the eleventh hour, to ban a 3,000-strong protest, fearing a wave of anti-Semitic attacks.Reuse content