Turns out, Brand has less than affable words in return for the current Mayor of the capital –uttered as he simultaneously confirmed he would "absolutely not" be considering running for the position in 2016.
Speaking to Jon Holmes in an interview with XFM radio, set to be broadcast tomorrow at 8am, Brand said: "Just hearing Boris Johnson there, you can see why people like him. He's a funny bloke, he's affable, he's got a nice way with him.
"But this is a time where a lot of Londoners are facing real fear about their homes. There's a real housing crisis. We've seen protesters at Earl's Court, we've seen on the Carpenters Estate, mum's having to organise not to be dispersed all over the country.
"Meanwhile Boris Johnson, the elected Mayor, elected to look after us, the people of London, takes five times more meetings with bankers than he does with civil servants, or representatives of the fire brigade, or any ordinary Londoner. You can see why, Jon, people might think… I think we've already got a comedian who's more known for his hair than his policies."
Holmes asked: "So this is a no, you're not going to do it
To which Brand replied: "Absolutely not. We've already got a comic in the job. If you want a daft comedian running London, just leave things as they are. What I'm interested in is real change."
Johnson had reacted to reports that suggested the comedian-turned-revolutionary was considering standing for the role on an independent "anti-politics" ticket in his column for The Telegraph.
"So much of this vituperation is obviously motivated by jealousy, of his success, his easy good humour, his string of beautiful and intelligent girlfriends, his Hollywood lifestyle, etc," he wrote.
"The second [reason for siding with Brand] is that he genuinely seems like a nice chap. A while ago he came to film Question Time in City Hall and made a good impression on everyone – chatting in the lift, introducing us to his mother etc – even if someone afterwards said that he did nip off to the gents for a long time."
Russell Brand's Most Controversial Quips
Russell Brand's Most Controversial Quips
1/19 On puberty:
“By puberty I learned that nothing worth having could be easily attained and to succeed one must be single minded."
2/19 On changing the world:
“I want to change the world, and do something valuable and beautiful. I want people to remember me before I'm dead, and then more afterwards.”
3/19 On being strong:
"Strength does not have to be belligerent and loud."
4/19 On grammar:
“I couldn't possibly have sex with someone with such a slender grasp on grammar!”
5/19 On manners in England:
"In England we have such good manners that if someone says something impolite, the police will get involved."
6/19 On junkie v vegetarian:
“Even as a junkie I stayed true [to vegetarianism] - 'I shall have heroin, but I shan't have a hamburger.' What a sexy little paradox.”
7/19 On the future:
“People don't realize that the future is just now, but later.”
8/19 On sex addiction:
“Boggle with sex addicts is up there with go-kart racing with junkies.”
9/19 On life:
“My life is just a series of embarrassing incidents strung together by telling people about those embarrassing incidents.”
Frazer Harrison/Getty Images
10/19 On happiness:
"If you want to be happy stop being so self-obsessed and start considering other people."
11/19 On drug addiction:
“The mentality and behavior of drug addicts and alcoholics is wholly irrational until you understand that they are completely powerless over their addiction and unless they have structured help, they have no hope.”
12/19 On sitcoms:
"I do have a regard for the musicality of language that came from BBC sitcoms like Fawlty Towers."
13/19 On life motivation:
"That's what keeps me alive, perversion and star quality.”
14/19 On love:
“When you fall in love you recognise you're not the most important person in the world, and your focus becomes another person.”
15/19 On threesomes:
“I like threesomes with two women, not because I'm a cynical sexual predator. Oh no! But because I'm a romantic. I'm looking for "The One." And I'll find her more quickly if I audition two at a time.”
16/19 On Conservatives:
"Conservatism appeals to our selfishness and fear, our designer and self-interest."
17/19 On surfing:
“Surfing should be called "foam-choking" or "sea stabbing.”
18/19 On Demi Moore:
"I've not made love to her yet, but it's a matter of time."
STEVE MORGAN/AFP/Getty Images
19/19 On success:
"When I was growing up, I thought I'd be a lot happier if I was famous and successful and if I had money."
Earlier today, and still on the seemingly endless publicity trail for his new book Revolution, Brand appeared on Radio 4's Today Show opposite Tom Sutcliffe, Susan Neiman, Juliet Barker and David Babbs.
During the programme, he again discussed his idea of "beautiful" democracy – a political framework built around self-supported communities and free from bureaucracy – and why he wouldn’t be voting in the UK’s next election.
"The reason I’ve not voted is because, like a lot of people in the country, 64 per cent in the last election we held, I don’t see who I’m supposed to vote for," he said.
"Ed Miliband? Clegg? The racist geezer? Cameron, the marginally less racist? They all come from the same schools, they all come from the same background. Now what I want is if these people are our leaders, if parliamentary democracy is going to be something that engages us, ordinary people, then it has to represent us. It has to represent us."
The speculation over the comedian’s possible foray into the world of politics came after he admitted he could be set to give up acting in order to focus on his revolutionary ideas.
It also followed an explosive appearance on Newsnight on Thursday, during which Brand said he was "open-minded" to suggestions that the US government orchestrated the 9/11 attacks.