The age girls hit puberty can be affected by both parents, study finds
Steve Connor is the Science Editor of The Independent and i. He has won many awards for his journalism, including five-times winner of the prestigious British science writers’ award; the David Perlman Award of the American Geophysical Union; four times highly commended as specialist journalist of the year in the UK Press Awards; UK health journalist of the year and a special merit award of the European School of Oncology for his investigations into the tobacco industry. He has a degree in zoology from the University of Oxford and has a special interest in genetics and medical science, human evolution and origins, climate change and the environment.
Wednesday 23 July 2014
The age of puberty in girls is affected by the kind of “imprinted” genes that they inherit from their mothers and fathers, suggesting that one or other of the parents has a bigger than expected influence on the age of a daughter’s sexual maturity.
Findings from an international study on more than 180,000 women identified 123 genetic variations associated with the timing of when girls experienced their first menstrual cycle.
Six of these variants were clustered within the imprinted regions of the genome which means they are switched on or off depending on whether they are inherited from the mother or the father.
“Normally, our inherited physical characteristics reflect a roughly average combination of our parents' genomes, but imprinted genes place unequal weight on the influence of either the mother's or the father's genes,” said John Perry of the Medical Research Council Epidemiology Unit at Cambridge University.
“Our findings imply that in a family, one parent may more profoundly affect puberty timing in their daughters than the other parent," said Dr Perry, the lead author of the study published in the journal Nature.
Some of the genes are only active when inherited from the father, some only active when inherited from the mother and as both types affect the timing of puberty, it indicates a “biological conflict between the parents over the child’s rate of development”, the study suggested.
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