Tuesday 26 August 1997
US researchers have worked out how the tuberculosis bacterium and leprosy, its biological cousin, invade cells - a finding that could open the way to new treatments. In Science, Washington University in St Louis reported that the bacteria hijack a protein left over from the natural breakdown of part of the immune system. They then use this to piggyback into macrophages - the "scavengers" of the immune system - where they eventually kill them. A vaccine or an antibiotic could introduce an antibody to block the connection between the complement breakdown protein, called C2a, and the bacteria. Tuberculosis currently infects one-third of the world's population, and kills 3 million a year. It is spreading once again in industrialised countries.
Among cancer researchers, the p53 tumour suppressor gene is a byword. But now they have found a close relation, p73. Reporting in Cell, a team led by Frank McKeon of Harvard Medical School report that p73 is found on the very tip of chromosome 1 - an area missing in many cancer cells. The discovery of p73, which also seems to be a tumour suppressor, could be significant in developing gene therapies.
New Labour, new House of Commons Select Committee on Science and Technology - and almost all have science or engineering qualifications. Included are five PhDs, a former ICI R&D manager, a food and biotechnology consultant and a former computer programmer - the Lib Dem Nigel Jones. In the past, the committee tended to include lawyers rather than scientists - reflecting the demographics of MPs rather than the population.
- 1 President of Argentina adopts Jewish godson to 'stop him turning into a werewolf'
- 2 Doctors remove 80 teeth from boy's jaw
- 3 The 'Black Museum': After 150 years, public set to see exhibits from police’s grisly crime museum
- 4 Stoke-on-Trent becomes first British city to be classified as 'disaster resilient' by the United Nations
- 5 Sir Winston Churchill’s family begged him not to convert to Islam, letter reveals
President of Argentina adopts Jewish godson to 'stop him turning into a werewolf'
The 'Black Museum': After 150 years, public set to see exhibits from police’s grisly crime museum
Downfall of Dustin 'Screech' Diamond, the 'Saved By The Bell' star charged with bar stabbing
Syrian teenager Usaid Barho reveals how he escaped from Isis using a suicide vest
Sir Winston Churchill’s family begged him not to convert to Islam, letter reveals
Millions of Britons struggling to feed themselves and facing malnourishment
British actor Idris Elba cannot star as James Bond because he is black, says shock jock Rush Limbaugh
Ukip member gets into Christmas spirit with Union Flag plea to Santa 'for our country back'
Germany anti-Islam protests: 17,000 march on Dresden against 'Islamification of the West'
Nigel Farage: Ukip leader named 'Briton of the year' by The Times
Immigrants make UK racist, says Ukip councillor Trevor Shonk
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