Tuesday 26 August 1997
US researchers have worked out how the tuberculosis bacterium and leprosy, its biological cousin, invade cells - a finding that could open the way to new treatments. In Science, Washington University in St Louis reported that the bacteria hijack a protein left over from the natural breakdown of part of the immune system. They then use this to piggyback into macrophages - the "scavengers" of the immune system - where they eventually kill them. A vaccine or an antibiotic could introduce an antibody to block the connection between the complement breakdown protein, called C2a, and the bacteria. Tuberculosis currently infects one-third of the world's population, and kills 3 million a year. It is spreading once again in industrialised countries.
Among cancer researchers, the p53 tumour suppressor gene is a byword. But now they have found a close relation, p73. Reporting in Cell, a team led by Frank McKeon of Harvard Medical School report that p73 is found on the very tip of chromosome 1 - an area missing in many cancer cells. The discovery of p73, which also seems to be a tumour suppressor, could be significant in developing gene therapies.
New Labour, new House of Commons Select Committee on Science and Technology - and almost all have science or engineering qualifications. Included are five PhDs, a former ICI R&D manager, a food and biotechnology consultant and a former computer programmer - the Lib Dem Nigel Jones. In the past, the committee tended to include lawyers rather than scientists - reflecting the demographics of MPs rather than the population.
Emergency call 'started off dumb, but got pretty serious'
Thought you'd seen it all after the Jeremy Paxman interview?
Argentinian scored 'rabona' wonder goal for Tottenham in Europa League – see it here
Far-right organisation has defended its actions on Facebook
- 1 This 'woman calls police to order pizza' story isn't going where you're expecting
- 2 Watch what happened when food critics were unknowingly served McDonald's
- 3 Jimmy Carr's controversial Oscar Pistorius joke goes a bit too far at the Q Awards
- 4 Ottawa shootings: Bruce MacKinnon's cartoon is the perfect tribute to soldier Nathan Cirillo
- 5 Of course, teenage girls need role models – but not like beauty vlogger Zoella
Isis releases first video showing the stoning of woman accused of committing adultery as her father shouts 'don't call me Dad'
FCKH8: Provocative anti-sexism video showing young girls swearing reinstated by YouTube
Diwali: What is the festival of lights – and how is it celebrated around the world?
Jimmy Carr's controversial Oscar Pistorius joke goes a bit too far at the Q Awards
Ottawa shootings: Bruce MacKinnon's cartoon is the perfect tribute to soldier Nathan Cirillo
Of course, teenage girls need role models – but not like beauty vlogger Zoella
Cameron is warned 'no possibility' of UK reducing immigration and that bid to bring in quota on migrant workers would be illegal
Support for EU membership 'at highest level since 1991' with most Brits wanting to stay 'in'
Thousands with degenerative conditions classified as 'fit to work in future' – despite no possibility of improvement
Residents should throw a street party and mix with immigrant neighbours, councils told
Attacks on 'Ukip Calypso' show how skewed people’s priorities are
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