Smoking doubles Alzheimer's risk
Friday 19 June 1998
The finding, from a study of almost 7,000 men and women, is surprising as previous research has suggested that smoking provided some protection against dementia.
In the new study, which is larger than earlier ones, doctors in the Netherlands selected men and women without dementia aged 55 or older. After two years, 146 had developed dementias of all kinds, of whom 105 had Alzheimer's disease which was confirmed by neuropsychological assessment and, in some cases, a brain scan.
In addition to the doubled risk of both dementia and Alzheimer's disease, smokers also tended to develop dementia at a younger age.
The researchers, who report their findings in the Lancet medical journal, found that smokers who carry the Apoe 4 gene, which has been linked with Alzheimer's, were at no greater risk of developing the disease than non- smokers. However, those without the gene were at four times the risk.
One explanation of why Apoe 4 might protect smokers is that smoking alters brain chemistry in a way that counters some of the effects of Alzheimer's disease. However, it is also possible that smokers with Apoe 4 die young, so do not live long enough to develop the disease, the researchers say.
- 1 Home Office says Nigerian asylum-seeker can’t be a lesbian as she’s got children
- 2 What happens to your body when you give up sugar?
- 3 Drugs Live cannabis trial: Hash is less harmful than any other drug, expert claims
- 4 Turkish Airlines flight TK 726 crash-lands on Nepal runway amid dense fog
- 5 Apple and Google users being spied on for a decade because of 'Freak' security flaw
The City of the Monkey God: Archaeologists claim to have found city lost for 1,000 years in remote Honduran jungle
Turkish Airlines flight TK 726 crash-lands on Nepal runway amid dense fog
Japanese island overrun with cats after population explodes
London property boom built on dirty money
Becky Watts: Stepbrother and his girlfriend named locally as two arrested on suspicion of murder
Durham Free School: 'Creationism taught at' free school facing closure
Nearly 100,000 of Britain's poorest children go hungry after parents' benefits are cut
Ukip would cut billions from Scottish budget to fund English tax cuts
End of the licence fee: BBC to back radical overhaul of how it is funded
Ukraine crisis: Top Chinese diplomat backs Putin and says West should 'abandon zero-sum mentality'
Boris Nemtsov shot dead: Outspoken Putin critic who had expressed fears for his life is killed near the Kremlin
£25000 - £35000 per annum: Recruitment Genius: This firm are focussed on assis...
£7 per hour: Recruitment Genius: A vacancy has arisen for a General Processor ...
£18000 - £22000 per annum: Recruitment Genius: A great opportunity has arisen ...
£14000 - £16000 per annum: Recruitment Genius: Full time and Part time positio...