Aspirin use may prevent cancer
Sunday 31 January 1993
When American scientists set out to discover the extent that aspirin reduced deaths from heart attacks, they found that among the aspirin-takers there were fewer deaths from bowel cancer.
Newcastle University researchers are about to embark on a Europe-wide project to see if prescribing aspirin could reduce the chance of getting bowel cancer.
The pounds 300,000 survey, funded by the EC, will cover 14 countries and follow 200 people, initially until the end of 1995. Half will take aspirin and half a placebo. All will be tested once a year.
To speed the survey, researchers will concentrate on a special group suffering from a rare genetic defect which makes them susceptible to bowel cancer, a condition known as polyposis.
John Burn, Professor of Clinical Genetics, said: 'If we just used a simple cross section of the population, most would be unlikely to develop polyps, or lumps on the lining of the large intestine, which can lead to cancer.'
Most people who develop bowel cancer do so in their late fifties or sixties. People with polyposis, caused by a defective gene known as the APC gene, tend to show the first signs of disease in their teens.
Professor Burn said: 'Normal people aren't affected by the cancer until later in life because the first, non-malignant stage is so long. With the APC gene defect, people miss out on that first stage. It's as if they go straight on to stage two, where the cells start to make mistakes as they divide, which can lead to malignancy.'
This form of cancer is treatable by removing a section of the large intestine. Aspirin could, in some cases, make surgery unnecessary, or delay it for several years.
- 1 Sabina Altynbekova, the girl branded 'too good looking' for volleyball, says social media obsession with her is a 'bit much'
- 2 Disney heiress Abigail disowns her share of family profits in West Bank company
- 3 Israel's propaganda machine is finally starting to misfire
- 4 Zayn Malik on Israel-Gaza: One Direction singer bombarded with Twitter death threats after posting #FreePalestine
- 5 'Hello mum, this is going to be hard for you to read ...'
Sally Farmiloe dead: Howards' Way actress, and former mistress of Jeffrey Archer, dies aged 60
Women in Turkey have a laugh in public at the deputy Prime Minister's expense
Sabina Altynbekova, the girl branded 'too good looking' for volleyball, says social media obsession with her is a 'bit much'
Disney heiress Abigail disowns her share of family profits in West Bank company
Australian model Robyn Lawley stages naked protest against huge coal mine seven times the size of Sydney Harbour
The secret report that helps Israel hide facts
Land for gas: Merkel and Putin discussed secret deal could end Ukraine crisis
Woman and two children killed by mob in riots over 'blasphemous' Facebook post in Pakistan
A day in the life of Vladimir Putin: The dictator in his labyrinth
Putin is 'thuggish, dishonest and reckless', says British ambassador to US
Richard Dawkins tweets: 'Date rape is bad, stranger rape is worse'
- < Previous
- Next >
Unpaid Voluntary Work : Cancer Research UK: We need motivational volunteers to...
£23000 - £25000 per annum: Ashdown Group: Accounts Assistant (Accounts Payable...
£200 - £300 per day: Ashdown Group: IT Trainer - Marlow, Buckinghamshire - £25...
£18000 - £30000 per annum + Generous commission scheme: AER Teachers: Thames T...