Aspirin use may prevent cancer
Sunday 31 January 1993
When American scientists set out to discover the extent that aspirin reduced deaths from heart attacks, they found that among the aspirin-takers there were fewer deaths from bowel cancer.
Newcastle University researchers are about to embark on a Europe-wide project to see if prescribing aspirin could reduce the chance of getting bowel cancer.
The pounds 300,000 survey, funded by the EC, will cover 14 countries and follow 200 people, initially until the end of 1995. Half will take aspirin and half a placebo. All will be tested once a year.
To speed the survey, researchers will concentrate on a special group suffering from a rare genetic defect which makes them susceptible to bowel cancer, a condition known as polyposis.
John Burn, Professor of Clinical Genetics, said: 'If we just used a simple cross section of the population, most would be unlikely to develop polyps, or lumps on the lining of the large intestine, which can lead to cancer.'
Most people who develop bowel cancer do so in their late fifties or sixties. People with polyposis, caused by a defective gene known as the APC gene, tend to show the first signs of disease in their teens.
Professor Burn said: 'Normal people aren't affected by the cancer until later in life because the first, non-malignant stage is so long. With the APC gene defect, people miss out on that first stage. It's as if they go straight on to stage two, where the cells start to make mistakes as they divide, which can lead to malignancy.'
This form of cancer is treatable by removing a section of the large intestine. Aspirin could, in some cases, make surgery unnecessary, or delay it for several years.
Emergency call 'started off dumb, but got pretty serious'
- 1 This 'woman calls police to order pizza' story isn't going where you're expecting
- 2 Axe wielding man shot dead after attacking four New York policemen on busy street
- 3 Watch what happened when food critics were unknowingly served McDonald's
- 4 Jimmy Carr's Oscar Pistorius joke goes a bit too far at the Q Awards
- 5 Ottawa shootings: Bruce MacKinnon's cartoon is the perfect tribute to soldier Nathan Cirillo
Renee Zellweger on plastic surgery rumours: 'I'm living a more fulfilling life and I'm thrilled that perhaps it shows'
FCKH8: YouTube reinstates provocative anti-sexism video showing young girls swearing
This 'woman calls police to order pizza' story isn't going where you're expecting
Axe wielding man shot dead after attacking four New York policemen on busy street
Jimmy Carr's Oscar Pistorius joke goes a bit too far at the Q Awards
Of course, teenage girls need role models – but not like beauty vlogger Zoella
Cameron is warned 'no possibility' of UK reducing immigration and that bid to bring in quota on migrant workers would be illegal
Support for EU membership 'at highest level since 1991' with most Brits wanting to stay 'in'
Thousands with degenerative conditions classified as 'fit to work in future' – despite no possibility of improvement
Residents should throw a street party and mix with immigrant neighbours, councils told
Attacks on 'Ukip Calypso' show how skewed people’s priorities are
£40000 - £50000 Per Annum Excellent benefits: Clearwater People Solutions Ltd:...
£30000 - £35000 Per Annum Excellent benefits: Clearwater People Solutions Ltd:...
£35000 - £40000 Per Annum Excellent benefits: Clearwater People Solutions Ltd:...
£47,334 - £59,058 per annum: Coventry University: The Centre for Agroecology, ...