Shrien Dewani, the man accused of arranging his wife’s murder on their honeymoon, is expected to be extradited to South Africa on Monday evening.
Following a long-fought battle against extradition, the 34-year-old will reportedly fly from London Heathrow airport and arrive in Cape Town on Tuesday morning, where he will be taken straight to a court hearing.
Millionaire businessman Dewani is accused of ordering the murder of his 28-year-old wife Anni, who was shot in November 2010 as the couple travelled in a taxi through the Gugulethu township during their honeymoon.
Dewani’s lawyers had argued that he should not be forced from the UK to face trial until he had recovered from mental health problems including depression and post-traumatic stress disorder.
But in March judges at the High Court rejected all his grounds for appeal against removal and denied him the chance to take the case to the Supreme Court.
The care home owner is expected to appear at Western Cape High Court in Cape Town for a brief hearing on Tuesday morning, and his mental health will then be assessed by a doctor.
Read more: Dewani suffers extradition setback
It is expected that he will be treated at the Valkenberg hospital while awaiting trial, and South African media have reported that security at the facility, where a number of notorious criminals are held, has been beefed up in anticipation of his arrival.
The family of Mrs Dewani welcomed the decision, saying it brought the prospect of justice a “step closer”.
Anish Hindocha, Mrs Dewani's brother, said there were “so many different” questions to be answered over his sister's death.
Wearing a picture of Mrs Dewani attached with a pink ribbon to his jacket, Mr Hindocha, appearing on ITV's Daybreak on Monday, spoke of the “nightmare” her family have endured over the past three years.
“It has been very difficult for my family. We are just focusing on this case at the moment and it is hard to even start making the grieving process final yet because there are so many questions we need answers to,” he said.
“It has been a nightmare, I can't sleep at night, I can't even work - the only focus I have is getting justice for her.
"We hope we get it and now today he is getting extradited and that is one step closer towards what we are seeking for her; that is justice for her."
Three men have already been convicted and jailed over Mrs Dewani’s s death, including taxi driver Zola Tongo, who was jailed for 18 years after admitting his role in the killing.
Dewani has always denied the charges and in a Panorama special earlier this year, the BBC suggested that Mrs Dewani could have been shot by mistake in a struggle and that there were significant contradictions in the account given by Tongo.
It also claimed that a soundtrack obtained from CCTV showed that hotel receptionist Monde Mbolombo, who has been granted immunity from prosecution, could have played a key role in what happened.
Mbolombo claimed that he had put Tongo in touch with the gunmen, but had no further involvement; however, questions have been raised over comments he was recorded making.
The Mail on Sunday revealed that, in an audio track taken from CCTV, he says: "This is how it's going to happen. Listen, don't give them it all up front. Give them what you've got on you so they don't come crying to you."
Xolile Mngeni, who prosecutors claim was the hitman, was convicted of premeditated murder over the shooting, and another accomplice, Mziwamadoda Qwabe, also pleaded guilty to murder and was jailed for 25 years.
Mrs Dewani’s uncle, Ashok Hindocha, also speaking on Daybreak , said: "We will be in South Africa when the case starts; tomorrow is just a formal procedure."
He said they did not mind if the trial was televised. He said his niece had become a "daughter of the world" and her family had received support from all over the globe, particularly Britain and South Africa.
"We want to know what happened to Anni, that is it," he said.
Additional reporting by Press Association