The 14th Congress of the European Society of Cardiology: Scientists find key to growing new arteries in hearts

HEART specialists believe that patients will be able to grow new heart arteries to relieve the congestion that causes attacks.

Scientists at Freiburg University in Germany have succeeded in growing new arteries in the hearts of rats, where none had been before, by implanting a human growth factor which is involved in the natural mechanism of wound-healing.

If the experiment is safe and works in man, it could mean a new era of non-surgical heart treatment. Instead of bypass surgery - in Britain, the commonest form of surgery for heart disease with about 15,000 operations conducted each year - the growth factor could be implanted through a catheter or injected on to the heart.

The scientists described how the laboratory had first identified the growth factor, a type of protein which initiates the growth of new blood vessels necessary for wound-healing. Then they genetically manipulated E coli bacteria to produce this angiogenetic growth factor and implanted it between the aorta, the major arterial vessel leading out of the heart, and the surface of the heart muscle. After nine weeks, they were able to see that new arteries had formed, creating bridges between aorta and the heart muscle.

Dr Roland Fasol, a member of the team, said that despite advances in knowledge and treatment, heart disease remained the big killer. 'The ultimate therapy is still coronary surgery, if conservative and conventional treatment fails. But the surgeon is faced with the problem of limited availability of his patients' own graft material for his operation.'

He said the experiment had proved the feasibility of the technique and further research is under way to test its safety and the permanence of the new blood vessels.

One concern is to make certain that the growth factors which promote rapid growth of cells do not, at the same time, encourage the growth of cancer cells. Kirsten Schlaudraff, head of the Freiburg laboratory, said that so far their angiogenetic growth factor showed no sign of encouraging cancer and it might be possible to try it in human heart patients in about three years time.

Start your day with The Independent, sign up for daily news emails
  • Get to the point
Latest stories from i100
Have you tried new the Independent Digital Edition apps?
Independent Dating
and  

By clicking 'Search' you
are agreeing to our
Terms of Use.

iJobs Job Widget
iJobs General

Ashdown Group: Front-End UI Application Developer

£30000 - £40000 per annum + Benefits: Ashdown Group: Front-End UI Application ...

Recruitment Genius: Digital Account Executive

£18000 - £26000 per annum: Recruitment Genius: They work with major vehicle ma...

Recruitment Genius: Service Engineers - Doncaster / Hull

£27000 per annum: Recruitment Genius: Domestic Service Only Engineers are requ...

Recruitment Genius: Employability / Recruitment Adviser

£23600 - £27500 per annum: Recruitment Genius: The Employability Service withi...

Day In a Page

Where the spooks get their coffee fix: The busiest Starbucks in the US is also the most secretive

The secret CIA Starbucks

The coffee shop is deep inside the agency's forested Virginia compound
Revealed: How the Establishment closed ranks over fallout from Loch Ness Monster 'sighting'

How the Establishment closed ranks over fallout from Nessie 'sighting'

The Natural History Museum's chief scientist was dismissed for declaring he had found the monster
One million Britons using food banks, according to Trussell Trust

One million Britons using food banks

Huge surge in number of families dependent on emergency food aid
Excavation at Italian cafe to fix rising damp unearths 2,500 years of history in 3,000 amazing objects

2,500 years of history in 3,000 amazing objects

Excavation at Italian cafe to fix rising damp unearths trove
The Hubble Space Telescope's amazing journey, 25 years on

The Hubble Space Telescope's amazing journey 25 years on

The space telescope was seen as a costly flop on its first release
Did Conservative peer Lord Ashcroft quit the House of Lords to become a non-dom?

Did Lord Ashcroft quit the House of Lords to become a non-dom?

A document seen by The Independent shows that a week after he resigned from the Lords he sold 350,000 shares in an American company - netting him $11.2m
Apple's ethnic emojis are being used to make racist comments on social media

Ethnic emojis used in racist comments

They were intended to promote harmony, but have achieved the opposite
Sir Kenneth Branagh interview: 'My bones are in the theatre'

Sir Kenneth Branagh: 'My bones are in the theatre'

The actor-turned-director’s new company will stage five plays from October – including works by Shakespeare and John Osborne
The sloth is now the face (and furry body) of three big advertising campaigns

The sloth is the face of three ad campaigns

Priya Elan discovers why slow and sleepy wins the race for brands in need of a new image
How to run a restaurant: As two newbies discovered, there's more to it than good food

How to run a restaurant

As two newbies discovered, there's more to it than good food
Record Store Day: Remembering an era when buying and selling discs were labours of love

Record Store Day: The vinyl countdown

For Lois Pryce, working in a record shop was a dream job - until the bean counters ruined it
Usher, Mary J Blige and Will.i.am to give free concert as part of the Global Poverty Project

Mary J Blige and Will.i.am to give free concert

The concert in Washington is part of the Global Citizen project, which aims to encourage young people to donate to charity
10 best tote bags

Accessorise with a stylish shopper this spring: 10 best tote bags

We find carriers with room for all your essentials (and a bit more)
Paul Scholes column: I hear Manchester City are closing on Pep Guardiola for next summer – but I'd also love to see Jürgen Klopp managing in England

Paul Scholes column

I hear Manchester City are closing on Pep Guardiola for next summer – but I'd also love to see Jürgen Klopp managing in England
Jessica Ennis-Hill: 'I just want to give it my best shot'

Jessica Ennis-Hill: 'I just want to give it my best shot'

The heptathlete has gone from the toast of the nation to being a sleep-deprived mum - but she’s ready to compete again. She just doesn't know how well she'll do...