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Video has emerged showing the aftermath of a hospital destroyed by an airstrike in northern Syria .
The air strike took place at a makeshift hospital in Maaret al-Numan; a province located 280 km north of Damascus.
The footage shows clouds of smoke and urgent screams are audible.
Doctors Without Borders (MSF) say they are unable to verify the footage.
An MSF spokeswoman told the Independent : "We can confirm that an MSF-supported structure in Marat Al Numan in Idlib, northern Syria was destroyed this morning in air strikes. We are currently gathering more information about the attack but have nothing more to share as yet."
The Britain-based Syrian Observatory for Human Rights said Russian warplanes targeted the makeshift hospital, destroying it and killing and wounding dozens.
Show all 19 1 /19In pictures: Russian air strikes in Syria In pictures: Russian air strikes in Syria Syrian boys cry following Russian air strikes on the rebel-held Fardous neighbourhood of the northern embattled Syrian city of Aleppo
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In pictures: Russian air strikes in Syria Russian defense ministry spokesman Major General Igor Konashenkov speaks to the media in Moscow, Russia. Konashenkov strongly warned the United States against striking Syrian government forces and issued a thinly-veiled threat to use Russian air defense assets to protect them
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In pictures: Russian air strikes in Syria Syrians wait to receive treatment at a hospital following Russian air strikes on the rebel-held Fardous neighbourhood of the northern embattled Syrian city of Alepp
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In pictures: Russian air strikes in Syria Russian Deputy Defense Minister Anatoly Antonov speaks at a briefing in the Defense Ministry in Moscow, Russia. Antonov said the Russian air strikes in Syria have killed about 35,000 militants, including about 2,700 residents of Russia
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In pictures: Russian air strikes in Syria Jameel Mustafa Habboush, receives oxygen from civil defence volunteers, known as the white helmets, as they rescue him from under the rubble of a building following Russian air strikes on the rebel-held Fardous neighbourhood of the northern embattled Syrian city of Aleppo
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In pictures: Russian air strikes in Syria Civil defence members rest amidst rubble in a site hit by what activists said were airstrikes carried out by the Russian air force in the town of Douma, eastern Ghouta in Damascus, Syria
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In pictures: Russian air strikes in Syria A girl carrying a baby inspects damage in a site hit by what activists said were airstrikes carried out by the Russian air force in the town of Douma, eastern Ghouta in Damascus, Syria
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In pictures: Russian air strikes in Syria Civilians and civil defence members look for survivors at a site damaged after Russian air strikes on the Syrian rebel-held city of Idlib, Syria
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In pictures: Russian air strikes in Syria Civilians and civil defence members carry an injured woman on a stretcher at a site damaged after Russian air strikes on the Syrian rebel-held city of Idlib, Syria
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In pictures: Russian air strikes in Syria Volunteers from Syria Civil Defence, also known as the White Helmets, help civilians after Russia carried out its first airstrikes in Syria
In pictures: Russian air strikes in Syria The aftermath of Russian airstrike in Talbiseh, Syria
In pictures: Russian air strikes in Syria Smoke billows from buildings in Talbiseh, in Homs province, western Syria, after airstrikes by Russian warplanes
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In pictures: Russian air strikes in Syria Russian Air Forces carry out an air strike in the ISIS controlled Al-Raqqah Governorate. Russia's KAB-500s bombs completely destroy the Liwa al-Haqq command unit
In pictures: Russian air strikes in Syria Caspian Flotilla of the Russian Navy firing Kalibr cruise missiles against remote Isis targets in Syria
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In pictures: Russian air strikes in Syria Russia claimed it hit eight Isis targets, including a "terrorist HQ and co-ordination centre" that was completely destroyed
In pictures: Russian air strikes in Syria A video grab taken from the footage made available on the Russian Defence Ministry's official website, purporting to show an airstrike in Syria
In pictures: Russian air strikes in Syria A release from the Russian defence ministry purportedly showing targets in Syria being hit
In pictures: Russian air strikes in Syria Russia launched air strikes in war-torn Syria, its first military engagement outside the former Soviet Union since the occupation of Afghanistan in 1979. Russian warplanes carried out strikes in three Syrian provinces along with regime aircraft as Putin seeks to steal US President Barack Obama's thunder by pushing a rival plan to defeat Isis militants in Syria
In pictures: Russian air strikes in Syria Caspian Flotilla of the Russian Navy firing Kalibr cruise missiles against remote Isis targets in Syria, a thousand kilometres away. The targets include ammunition factories, ammunition and fuel depots, command centres, and training camps
© TASS/ITAR-TASS Photo/Corbis
The airstrike comes after world powers agreed to a "cessation of hostilities" in Syria after talks in Munich .
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