Chasing 208 for 6, South Africa looked to be in control after 40 of their 50 overs with 159 on the board and eight wickets in hand. Waqar then struck, bowling the opener Andrew Hudson for 93 and Daryl Cullinan for a duck two balls later.
Hudson was the top scorer in the match but, with Kepler Wessels and Peter Kirsten already back in the pavilion, panic set in and Jonty Rhodes, Brian McMillan and Dave Richardson threw away their wickets by being run out.
South Africa had put Pakistan in on a damp pitch and Allan Donald, South Africa's main contribution to the array of fast bowling talent on display in a series which also includes the West Indies, dismissed Saeed Anwar in the first over before he had scored.
Pakistan quickly settled down, though, Imzamam-ul-Haq scoring 47 before being run out and Asif Mujtaba making an unbeaten 49.
TOTAL INTERNATIONAL SERIES (Durban): Pakistan 208 for 6. South Africa 198 (A C Hudson 93; Waqar Younis 5-25). Pakistan win by 10 runs.Reuse content