The United manager has a striking dilemma up front, with Ole Gunnar Solskjaer also having treatment on an ankle injury after being left out of the squad on Wednesday. Ferguson could be forced into using last season's strike force of Teddy Sheringham and Andy Cole.
Middlesbrough, for whom Gary Pallister makes what is likely to be an emotional return to Old Trafford, are waiting for fitness tests on Gianluca Festa, Curtis Fleming, Phil Stamp, Mark Summerbell and Brian Deane.
MANCHESTER UNITED (from): Schmeichel, Brown, Stam, G Neville, Irwin, Beckham, Keane, Scholes, Giggs, Cole, Solskjaer, Sheringham, Blomqvist, Butt, Johnsen, P Neville, Greening, Van der Gouw.
MIDDLESBROUGH (from): Schwarzer, Roberts, Fleming, Gordon, Stockdale, Pallister, Cooper, Vickers, Festa, Mustoe, Townsend, Summerbell, Rickard, Deane, Beck, Blackmore, Kinder, Harrison.
Referee: N Barry.Reuse content