Arsene Wenger has made three changes from Arsenal's 2-2 draw with Hull City on Saturday for tonight's Champions League tie at Anderlecht.
With goalkeeper Wojciech Szcesny suspended, third-choice Emiliano Martinez comes in to make third start for the club.
Elsewhere, Calum Chambers comes in for Hector Bellerin at right-back, and Aaron Ramsey replaces Alex Oxlade-Chamberlain in midfield. It is Ramsey's first start since late September after injuring his hamstring.
Arsenal: Martinez, Chambers, Mertesacker, Monreal, Gibbs, Flamini, Sanchez, Wilshere, Ramsey, Cazorla, Welbeck
Subs: Huddart, Bellerin, Rosicky, Arteta, Oxlade-Chamberlain, Podolski, Campbell
Anderlecht team to follow...
Anderlecht vs Arsenal stats
Arsenal are in the group stage of the Champions League for the 17 consecutive season, but have failed to go beyond the round of 16 for the last four years.
The Gunners are second in Group D following 2-0 away defeat to Dortmund and a 4-1 home win against Galatasaray.
Anderlecht have only managed two points in eight Champions League games.
Since reaching the round of 16 in 2000/01 the Belgian Champions have finished bottom of their group seven times.
- More about: