The Europa League quarter-final draw saw holders Sevilla matched against Andre Villas-Boas' Zenit St Petersburg.
Sevilla, who beat Benfica on penalties to lift the title last season, beat Zenit 5-2 on aggregate at the same stage in 2006 when the Spanish side went on to win the competition.
In-form Wolfsburg take on Rafa Benitez's Napoli, having knocked out another Italian opponent in the previous round, beating Inter Milan 5-2 on aggregate.
Dynamo Kiev, who dumped out Everton in the round of 16, will face Tottenham's conquerors Fiorentina.
Ukraine's Dnipro Dnipropetrovsk, making their first ever appearance at this stage of the tournament, take on Belgium's Club Brugge, who are the only unbeaten side left in the competition.
The first legs will be played on April 16 with the second legs a week later on April 23.
Europa League Draw
Sevilla (Spain) vs Zenit (Russia)
Dnipro (Ukraine) vs Bruges (Belgium)
Dynamo Kiev (Ukraine) vs Fiorentina (Italy)
Wolfsburg (Germany) vs Napoli (Italy)
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