Sevilla will take on Primera Division rivals Valencia in the semi-finals of the Europa League, with Benfica and Juventus going head to head in the other last-four encounter.
Unai Emery's in-form Sevilla side coasted into the semi-finals with a 4-1 win over Porto at the Ramon Sanchez Pizjuan stadium to progress 4-2 on aggregate and secure the coach a tie against his former club.
Emery led Valencia to three top-three finishes in the Primera Division before leaving the Mestalla in 2012.
Valencia booked their place in the semi-finals with a remarkable comeback to beat Basle 5-0 on Thursday, overturning a 3-0 first-leg deficit.
Benfica stepped up their pursuit of a first European trophy for over 50 years with a 3-0 aggregate success against AZ Alkmaar, while Juventus edged Lyon 2-1 to advance 3-1 overall.