The Manchester United winger Ashley Young is the latest player to have to pull out of Roy Hodgson's squad for the first two World Cup qualifiers against Moldova and Ukraine with a knee injury picked up last weekend.
Young, a regular for Hodgson, hurt his knee against Fulham last Saturday, an injury that necessitated his substitution in the game.
The 27-year-old had treatment again on the problem yesterday and while it is not expected to be a long-term problem, it was felt that there would be no way he could play in the game against Moldova, in Chisinau, a week today.
There are no major surprises in Hodgson's squad for the crucial two opening World Cup qualifiers.
Wayne Rooney misses the games with injury but John Terry is back in the squad. Robert Green has been left out, with Jack Butland and John Ruddy the two reserve goalkeepers to Joe Hart.
Despite having been told that he is not needed at Liverpool by the manager Brendan Rodgers, Andy Carroll keeps his place in the squad. Of the other strikers, Danny Welbeck, Daniel Sturridge and Jermain Defoe, only Defoe can claim to be an automatic first choice for his club side at the moment and that may well have changed now with the arrival of the Togo striker Emmanuel Adebayor on a permanent deal at Tottenham Hotspur.
Goalkeepers Jack Butland, Birmingham, Age: 19 Caps: 1; Joe Hart, Man City 25/22; John Ruddy, Norwich 25/1
Defenders Leighton Baines, Everton 27/9; Ryan Bertrand, Chelsea 23/1; Gary Cahill, Chelsea 26/10; Ashley Cole, Chelsea 31/98; Phil Jagielka, Everton 30/13; Glen Johnson, Liverpool 28/40; Joleon Lescott, Man City 30/21; John Terry, Chelsea 31/77; Kyle Walker, Spurs 22/3
Midfielders Michael Carrick, Man United 31/23; Tom Cleverley, Man United 23/1; Alex Oxlade-Chamberlain, Arsenal 19/5; Steven Gerrard, Liverpool 32/96; Adam Johnson, Sunderland 25/12; Frank Lampard, Chelsea 34/91; James Milner, Man City 26/31
Forwards Theo Walcott, Arsenal 23/28; Andy Carroll, Liverpool 23/8; Jermain Defoe, Spurs 29/49; Daniel Sturridge, Chelsea 22/2; Danny Welbeck, Man United 21/9