Nathaniel Clyne will make his England debut and Wayne Rooney will win his 100th cap when the Three Lions face Slovenia.
It is unclear whether Roy Hdogson will stick with the diamond formation, though it seems likely as he has made just two changes, both at full-back.
The Southampton right-back comes in for Arsenal's Calum Chambers, with Kieran Gibbs replacing the injured Leighton Baines.
Gibbs wins just his fourth cap in this match, as England look to make it four wins out of four in Group E.
For the visitors, Srecko Katanec has also made just two changes to the team that beat Lithuania 2-0.
Maribor midfiedler Ales Mertelj and former AC Milan winger Valter Birsa come into the side.
England: Hart, Clyne, Cahill, Jagielka, Gibbs, Henderson, Wilshere, Lallana, Sterling, Welbeck, Rooney.
Subs: Smalling, Foster, Chambers, Barkley, Milner, Chamberlain, Walcott, Downing, Berahino, Lambert, Forster.
Slovenia: Handanovic, Brecko, Cesar, Ilic, Struna, Kurtic, Mertelj, Birsa, Kirm, Kampl, Novakovic.
Subs: To follow