The Swiss, who has been in charge of world football's governing body since 1998, only won a fifth term as president last week. However allegations of corruption and arrests of top officials have taken their toll, leading to his decision.
“I will organise extraordinary congress for a replacement for me as president,” said the 79-year-old. “I will not stand. I am now free from the constraints of an election. I will be in a position to focus on profound reforms. For many years we have called for reforms. But these are not sufficient.
“We need a limitation on mandates and terms of office. I have fought for these changes but my efforts have been counteracted.”
Any new elections cannot take place until December at the earliest, with a time-frame of between December and March 2016 put on the search for a new successor.
So who might be the next president of Fifa? We take a look at the candidates...
Contenders to replace Sepp Blatter as Fifa president
Join our commenting forum
Join thought-provoking conversations, follow other Independent readers and see their replies