Arsenal v Fulham
If Arsenal win tomorrow they confirm third place, but defeat could let in Spurs.
Aston Villa v Blackburn
Villa could steal fifth place from Manchester City if they win and Roberto Mancini's side lose at West Ham.
Burnley v Tottenham
Fresh from Wednesday's celebrations at Eastlands, Spurs could finish third, and clinch automatic Champions League qualification, if they win and Arsenal lose.
Chelsea v Wigan
Aside from the title race, Didier Drogba will be desperate to get on the scoresheet as he is currently tied on 26 goals with Wayne Rooney as the Premier League's top scorer this season.
Manchester United v Stoke
At the heart of the title drama , but United are also vying with Chelsea for the most League clean sheets this season, while Rooney has his eye on the Golden Boot.
West Ham v Man City
Not quite the Champions League, but City should clinch fifth place with a draw at the now-safe Hammers.
Brentford v Hartlepool
Rocked this week by being docked three points for fielding a suspended player, Hartlepool must win at mid-table Brentford to be certain of avoiding relegation.
Exeter v Huddersfield
Only goal difference separates Exeter and Tranmere in the relegation zone. Paul Tisdale's side need a win to stay up but Huddersfield have a slender chance of automatic promotion.
Leeds United v Bristol Rovers
After looking certain for so long of ending their stay in League One, Leeds have stuttered badly in recent months and must win at Elland Road today to be certain of going up. Rovers will be tough opponents, though.
Millwall v Swindon
Both sides are locked together a point behind Leeds and will be going all out for a win while hoping for good news from Elland Road.
Oldham v Charlton
A freak set of results – Leeds losing, Millwall and Swindon drawing – would take Charlton up, provided they beat managerless Oldham.
Stockport v Tranmere
Tranmere need to do better than Exeter, or win while Hartlepool only draw or Gillingham lose, to stay up. Fortunately, bottom-club Stockport should offer scant resistance.
Wycombe v Gillingham
The Gills have yet to win away this season – but a point at already relegated Wycombe should be enough to send someone else down.
Barnet v Rochdale
Barnet are on a wretched run of form, hardly good preparation to face promoted Rochdale in a game they must win to be certain of avoiding slipping back into the Blue Square Premier.
Burton Albion v Grimsby
Win or bust for Grimsby if they are to pull off the great escape and clamber clear of relegation.
Cheltenham v Accrington
Cheltenham can still go down if they lose heavily and both Grimsby and Barnet win.
Darlington v Dagenham
The Daggers can hold on to the final play-off spot with a win in the last League game for a while at the Northern Echo Arena.
Morecambe v Aldershot
The last game at Christie Park, if Morecambe fail to reach the play-offs. A win will clinch a top-seven place.