First red card offence - stamping on Gareth Southgate, 1995
Two years after completing his British record £3.75m move to Old Trafford, Keane's first red card came about in typically low-key fashion.
Gareth Southgate, awkwardly his current studio partner on ITV Sport, was deemed to require severe 'Keano' punishment after a rash challenge in 1995. Unlike most players, who would have allowed the ref to take action, the United ace opted to stamp the Crystal Palace defender in the privates. Twice.
Sent off for Republic of Ireland vs. Russia, 1996
Perhaps it was inevitable that Keane and Mick McCarthy would never get on. In the Irishman's first game in charge he extended an arm of friendship by handing the midfielder, with thirty caps to his name, the captain's armband.
In Keane's delicate way of putting it, he repaid his manager's faith after getting "sent off for kicking a Russian."
Won the PFA and Football Writer's Football of the Year Awards, 2000
After another brilliant season for Manchester United, Keane was starting to make headlines for the right reasons. At the awards ceremony in London he even launched a remarkable defence of his oldest foes, those pesky interfering match officials.
"Referees are human," he said. "They are going to make mistakes. I think there should be more tolerance. Hopefully we will give referees a bit of a break next season." That stance, I'm sure you're mortified to hear, didn't last long.
Criticising the Manchester United supporters, 2000
Despite progressing into the next round of the Champions League, courtesy of a narrow 1-0 win over Dynamo Kiev, Keane was flustered by what he perceived as a lack of support from the home fans.
Homing in on those in the executive boxes in particular he said: "I don't think some of the people who come to Old Trafford can spell football, never mind understand it."
Taking revenge on Alf-Inge Haaland, 2001
Less than twelve months after pledging to help referees, Keano decided that the best way to do so would be to carry out his own law enforcement regime.
After being seriously hurt by an innocuous Alf-Inge Haaland tackle in 1997 - and rendered injured for the rest of that season - Keane didn't forget to repay his debt. When asked, years later, whether or not he regretted his subsequent revenge, he laughed: "Not for two weeks' wages, no!"
Sent home from the World Cup after a fall-out with McCarthy, 2002
After arriving in Asia for the 2002 World Cup, Keane was again less than impressed. This time it was about the facilities at the Irish camp in Saipan but, instead of talking things over with McCarthy, he again opted for the more dramatic option.
In front of the entire Irish side, during a routine team meeting, he berated his manager. "I didn't rate you as a player, I don't rate you as a manager, and I don't rate you as a person," he said in the polite version of events. He was later extradited from the camp.
Uses MUTV to launch an attack on his United colleagues, 2005
In just one of many clashes with Keane detailed in Sir Alex Ferguson's autobiography, he opens the lid on perhaps the final straw on the camel's back at Old Trafford. That must have been one muscular camel.
Speaking on the in-house television channel MUTV, Keane took the time to list his less-than-savoury views of his teammates. "The hardest part of Roy's body is his tongue," Ferguson writes - etching a delightful image onto the eyes.
First foray into management at Sunderland, 2006
Things started well for the Football League's newest manager as Roy Keane led his Sunderland side from the bottom of the Championship right up to the top in just one season.
Things soon turned sour however as the 'Manager of the Year' during their promotion season spent a small fortune at the Stadium of Light the following summer. 'One of the worst and longest nights' of his career against Northampton in the League Cup proved to be a sign of things to come. His beard grew and, so legend says, he was duly sacked.
Tumultuous time with Ipswich Town, 2009
That beard, long associated with the weeks which lead to Keane getting the sack, was to make another appearance at Portman Road after his side finished 19th in his first full season with Ipswich.
In those dark final days Keane treated one lucky journalist to his famous death stare when he was asked about his future. "I refuse to answer that question," Keane whispered in reply. His eyes did all the talking.