Danny Welbeck's thigh injury could leave Arsene Wenger with a lack of options up front for the crucial New Year's Day clash with Southampton.
The Arsenal and England striker, who has seven goals in all competitions this season, will face a late fitness test after hurting himself in the win at West Ham on Sunday.
With Olivier Giroud serving the second of a three-match ban for headbutting Queens Park Rangers defender Nedum Onuoha, Wenger may have to turn to Yaya Sanogo - who has been struggling with injury himself - or out of favour Lukas Podolski, who is linked with a January move away from the Emirates.
Joel Campbell, yet to start a Premier League game, is another option.
Theo Walcott has been an unused substitute for each of the last three games, but has not played in the Premier League since his 12 minutes against Swansea on 9 November.
Wenger could also deploy star man Alexis Sanchez through the middle, with one of the above joining Alex Oxlade-Chamberlain on the wing.
Arsenal's injury list
Arsenal's injury list
1/5 Mikel Arteta (midfield)
Like Diaby, the Spaniard is closing in on a return but the Swansea match will come to soon. The club captain last played in November.
2/5 Mathieu Debuchy (defender)
Returned in the FA Cup semi-final win over Reading but has since been ruled out with injury and Wenger confirmed he remains 'unavailable'.
3/5 Alex Oxlade-Chamberlain (midfield)
Suffered a hamstring injury against Manchester United in the FA Cup and hasn't played since as it has exacerbated a groin problem. Out at least until May and facing surgery in the summer.
4/5 Aaron Ramsey (midfield)
Aaron Ramsey caught a kick on his calf during the win over Hull and was later substituted. The Welshman was rated 50/50 for the Swansea match by Wenger, but it now appears that he is a major doubt for the clash at the Emirates.
5/5 Danny Welbeck (forward)
Danny Welbeck has not played since the goalless draw with Chelsea towards the end of April after suffering a knee injury. Wenger has confirmed that the injury is 'nothing major', and that he should return to full fitness before the end of the season.
Jack Wilshere, Mikel Arteta and Aaron Ramsey remain sidelined, though the Welshman may be deemed fit enough to play at St Mary's.Reuse content