New Crystal Palace manager Alan Pardew gave Glenn Murray his first Barclays Premier League start of the season as the Eagles hosted Tottenham.
The 31-year-old Murray spent much of this season on loan at Reading and kept his place in attack, lining up alongside Dwight Gayle at Selhurst Park.
Julian Speroni, James McArthur and Jason Puncheon were the changes to last weekend's FA Cup win at non-league Dover - Pardew's first match at the helm.
Mousa Dembele and Benjamin Stambouli replaced Ryan Mason and Nabil Bentaleb in the Spurs side as head coach Mauricio Pochettino made two alterations to the New Year's Day victory over Chelsea.
Crystal Palace: Speroni, Kelly, Dann, Delaney, Ward, Bannan, McArthur, Ledley, Puncheon, Murray, Gayle.
Subs: Mariappa, Hangeland, Guedioura, Campbell, Zaha, Hennessey, Thomas.
Tottenham Hotspur: Lloris, Walker, Fazio, Vertonghen, Rose, Stambouli, Dembele,
Townsend, Eriksen, Chadli, Kane.
Subs: Kaboul, Lennon, Paulinho, Soldado, Vorm, Capoue, Davies.
Referee: Anthony Taylor (Cheshire)