Liverpool manager Brendan Rodgers believes striker Daniel Sturridge is the fittest he has been for 18 months, but will still handle him with caution.
The England striker, who spent most of the summer undergoing rehabilitation in the United States, returned to full training with the rest of the squad this week after recovering from a hip operation in May.
He will not be ready for Saturday's match against Manchester United at Old Trafford but his impending return will boost a goal-shy squad which has scored just two goals in four matches and none in their last two.
Manchester United vs Liverpool combined XI
Manchester United vs Liverpool combined XI
1/10 GK: David De Gea
He hasn't even played this season, but De Gea goes straight into our side ahead of United team-mate Sergio Romero and Liverpool's Simon Mignolet. With the transfer window closed and his proposed move to Real Madrid over for now, Van Gaal is expected to bring the Spain international back into the fold and there's no question he's the best goalkeeper of the lot.
2/10 RB: Matteo Darmian
Arguably the toughest dilemma of the lot comes at right-back, with Darmian and Nathaniel Clyne both impressing so far this term. The nod goes to the United defender by a whisker based on how quickly the Italian has managed to resolve what has been a problem position for United for some time.
3/10 CB: Chris Smalling
For all the speculation over Manchester United signing a centre-back during the summer, Smalling has shown that the need for reinforcements isn't as great as some feared. The England international has been consistent and appears to be growing in confidence all the time. It means there's no place for Dejan Lovren, who in contrast appears to be regressing from the player Liverpool spent £20m to sign.
4/10 CB: Martin Skrtel
Thankfully for Liverpool, Skrtel has looked good this term, and beats Daley Blind to the other centre-back berth. United's Dutch midfielder/defender/full-back is still new to the central position.
5/10 LB: Luke Shaw
Joe Gomez has made an unexpectedly impressive start to his Anfield career, with the 18-year-old playing in every game since joining from Charlton. But Shaw has begun to show why Manchester United were willing to take such a huge gamble on a teenager, being solid defensively and a threat going forward.
6/10 M: Bastian Schweinsteiger
The World Cup winner is beginning to show why, despite concerns over his fitness, he's been among the best midfielders in Europe over recent years. With Michael Carrick injured, he'll be wanting to impress during a potential run in the starting line-up. He beats Adam Lallana to a place, with the Liverpool midfielder also only starting two games so far this term.
7/10 M: Morgan Schneiderlin
The former Southampton player has impressed in the centre of the park with his passing and ability to disrupt the opposition. James Milner, one of only two Liverpool midfielders to start every match this term is yet to set the world alight following his free transfer from Manchester City.
8/10 M: Memphis Depay
The young Netherlands international looks to be showing more ability and growing in confidence with each match and his recent European double offered a glimpse of the big future the summer signing could have at Old Trafford. It means there is no place for Roberto Firmino, one of Liverpool's big summer signings.
9/10 ST: Wayne Rooney
Rooney is still to score in four Premier League games, but his two-in-two for England and hat-trick in Europe indicates the striker is hitting form. However, he only makes it into the side because Coutinho, who has been Liverpool's best player so far this season, is suspended for Saturday's game.
10/10 ST: Christian Benteke
Joining Rooney in attack is Benteke. With just the one goal to his name the former Aston Villa player hasn't exactly been prolific, but he has been causing opposing defences a headache, particularly in the 0-0 draw with Arsenal. With Daniel Sturridge still out, Benteke will hope to begin writing himself into Anfield folklore with a goal at Old Trafford.
"There is no timeline as to when he will be fit to participate in the game but he is obviously back in training, which is good," said Rodgers.
"He looked really sharp in training, probably the best he's looked fitness-wise for 18 months, and it will be really good when he gets back.
"I can never say that (he is over the worst of his injuries) because I don't want to sit here and something happens in a couple of months' time.
"I can only look at what I see and from my experiences in the past I don't want to put any timeline on him coming back.
"I am grateful for the work done in America, for our own medical team who have done a brilliant job to do everything they possibly could to get Daniel back to a level of fitness.
"He has worked hard. He has joined in with the group and we will take it from there, day-by-day."
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