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Ahead of the match at Upton Park, we take a look at how the sides' players Diafra Sakho and Radamel Falcao compare.
The Hammers have found little joy against United on their own patch, with one win against them in eight years.
Five places and seven points separate the sides at present, United in third and West Ham sitting in an impressive eighth position in the top flight.
Manager Sam Allardyce’s outfit have fallen to a solitary defeat at home in ten home league fixtures although they have picked up just one win in six games.
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