The Saints knocked Arsenal out of the Capital One Cup at the Emirates, thanks to Nathaniel Clyne’s long range screamer.
Arsenal will be out for revenge – and the win could cast the Gunners within three points of the third-placed Saints.
KICK-OFF: Wednesday, 7.45pm
PAST THREE MEETINGS…
Arsenal 1 (Sanchez) Southampton 2 (Tadic, Clyne), Capital One Cup Third Round, September 2014
Southampton 2 (Fonte, Lallana) Arsenal 2 (Giroud, Cazorla), Premier League, January 2014
Arsenal 2 (Giroud 2) Southampton 0, Premier League, November 2013
Arsenal will be looking for a repeat of their 6-1 home victory in September 2012
Arsenal have 44 wins over Southampton overall – compared to the Saints’ measly 17 wins.
Arsenal are unbeaten in their last nine Barclays Premier League games against Southampton (W5 D4).
Arsene Wenger has come up against Ronald Koeman on seven occasions, winning just one match, drawing four and losing two.
Southampton’s three PL defeats this season have all come against sides that finished in the top six of the 2013-14 Premier League table (Man City, Liverpool and Tottenham). Arsenal finished fourth last season.
Arsenal to win: 1.8
Southampton to win: 4.8
TV: Live on Sky Sports 1 at 7.45pm, highlights on BBC One at 10.35pm.Reuse content