Premier League injury news: Who's in and who's out this weekend? Arsenal lacking defenders but Newcastle the worst hit with up to 10 missing

Swansea and Tottenham have the fewest players on the treatment table

Arsene Wenger has come under intense pressure this season (Getty Images)

Alan Pardew will be struggling when Newcastle visit Arsenal on Saturday, with the manager having up to 10 senior players missing.

Newcastle, who ended Chelsea's 23-match unbeaten run last weekend, will be hoping to continue their fine run of form with another victory at the Emirates, but Pardew will be forced to start young goalkeeper Jak Alnwick, with both Tim Krul and Rob Elliott likely to be out until January.

Alnwick, 21, played the second-half against the Blues last Saturday, pulling off an important save from Diego Costa as time was winding down at St James' Park.

Club captain Fabricio Coloccini and Mehdi Abeid both face late fitness tests to face Arsenal, while Ryan Taylor, Gabriel Obertan and Davide Santon remain sidelined.

Arsenal will have seven players missing for the same game, with Mathieu Debuchy likely to play at centre-back on his return to Premier League action after missing the last three months.

Aaron Ramsey, Jack Wilshere, Mesut Ozil and Theo Walcott will also miss the game.

Louis van Gaal's injury struggles continue, with Chris Smalling and Phil Jones out, although Jonny Evans did return against Southampton. Angel Di Maria has also been ruled out of the game but Rafael could return for the clash with bitter rivals Liverpool at Old Trafford. Brendan Rodgers will still be without Daniel Sturridge but Mario Balotelli could play for the first time in a month.

Aston Villa could also have eight players, though three of those face late fitness tests.

Tottenham have just one player missing, Kyle Naughton, with Kyle Walker making his first appearance in nine months in the 1-0 defeat to Besiktas on Thursday night.