Managerless Queens Park Rangers travel to the Stadium of Light on Tuesday evening second bottom of the Premier League and having lost all 11 of their away games this season.
A late winner from Sadio Mane of Southampton on Saturday consigned Rangers to their fourth consecutive Premier League defeat in their first outing since Harry Redknapp resigned last Tuesday. Academy coach Chris Ramsey has been put in charge as interim manager as the search for a new boss continues.
Sunderland sit five points ahead of the visitors and new signing Jermaine Defoe has scored twice in the Premier League since his January arrival, including a strike in the 1-1 draw against Swansea on Saturday.
However, the Black Cats are only four points away from the relegation zone and a defeat on Tuesday would cut the gap between the sides to two points.
KICK-OFF: Tuesday, 7.45pm
Queens Park Rangers 1 (Austin) Sunderland 0, Premier League, August 2014
Queens Park Rangers 3 (Remy, Townsend, Jenas) Sunderland 1 (Fletcher), Premier League, March 2013
Sunderland 0 Queens Park Rangers 0, Premier League, November 2012
Sunderland have thrown away 14 points from leading positions this season, a figure only surpassed by Swansea and Everton.
Sunderland have scored only six goals in their last eight Premier League home games.
QPR are the first team to lose their first 11 away games in a top-flight season since Liverpool in 1953/54.
QPR are the only Premier League side not to score a goal in the opening 15 minutes of a match this season.
Sunderland to win: 1.9
Queens Park Rangers to win: 3.9
TV: Highlights on BBC One at 10.45pm on Wednesday.