QPR are still awaiting their first win of the season after the 1-1 draw against Aston Villa in Harry Redknapp's first home game in charge last weekend.
With Wigan without the suspended Maynor Figueroa and Gary Caldwell the R's will see this as the ideal opportunity to pick up maximum points and collect their first away win in over a year - the last came against Stoke in a 3-2 win last November.
Following their 3-0 defeat to Newcastle on Monday night the Latics lie in 16th place, just two points above the bottom three, and will see the game against Rangers as an ideal opportunity to get back to winning ways.
KICK-OFF: Saturday, 3pm
PAST THREE MEETINGS…
QPR 3 (Helguson, Buzsaky, Smith) Wigan 1 (Rodallega), Premier League, January 2012
Wigan 2 (Di Santo 2) QPR 0, Premier League, August 2011
Wigan 0 QPR 0, Premier League, April 2005
QPR remain the only team in England without a win this season.
Rangers have lost 60 per cent of their games this season.
The west London side last won an away game over a year ago - defeating Stoke City 3-1 at the Britannia.
Wigan have a win percentage of 27 per cent from their Premier League fixtures this season.
QPR last won at the DW Stadium (then known as the JBB stadium) 11 years ago.
Wigan to win: 2.44
QPR to win: 3.15
TV: Highlights on BBC1 at 10.30pm