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Ahead of the match at the Etihad Stadium, we take a look at how the sides' forwards Sergio Aguero and Diego Costa compare.
Manchester City will need to pick themselves up after a last-gasp Champions League defeat at Bayern Munich on Wednesday.
Manuel Pellegrini’s side have now not won any of their last three games, so the visit of a thus far invincible Chelsea has come at a difficult time for the Sky Blues. Edin Dzeko has not found the net all season, so Pellegrini will look to Sergio Aguero who already has three goals this campaign.
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