Tottenham head coach Mauricio Pochettino recalled in-form Harry Kane as one of six changes for the visit of London rivals West Ham.
Kane was a substitute for Thursday's 1-1 Europa League draw with Fiorentina but the striker was back in the side, along with Eric Dier, Danny Rose, Ryan Mason, Mousa Dembele and Erik Lamela - with Christian Eriksen and Nacer Chadli amongst those dropped to the bench.
West Ham have won only once in the Premier League since Christmas but made only one alteration from their 4-0 FA Cup fifth-round defeat at West Brom as fit again Winston Reid came in for captain Kevin Nolan - with Cheikhou Kouyate moved back into a more familiar midfield role.
Tottenham Hotspur: Lloris, Walker, Dier, Vertonghen, Rose, Mason, Bentaleb, Townsend, Dembele, Lamela, Kane.
Subs: Soldado, Vorm, Fazio, Chadli, Eriksen, Stambouli, Davies.
West Ham: Adrian, Jenkinson, Reid, Tomkins, Cresswell, Noble, Song, Kouyate, Downing, Valencia, Sakho.
Subs: Nolan, Jarvis, O'Brien, Collins, Demel, Jaaskelainen, Cole.Reuse content