Widnes had a painful lesson in the harsh realities of Super League as they were thrashed 66-6 at Huddersfield in their first away fixture.
The Giants did the damage out wide, with Leroy Cudjoe claiming four tries – one of them a length-of-the-field effort – and Luke George three.
Bradford had a surprise 20-12 win at Castleford, with early tries from Jarrod Sammut and Tom Burgess, plus a late one from Brett Kearney.
Hull KR were also away winners, 22-10 at Wakefield, despite losing their scrum-half, Michael Dobson, with a suspected broken collarbone.
After disappointing badly in their first game against Huddersfield, Wigan got their season started on Saturday night with a convincing 20-6 victory over the champions Leeds.
Three tries from Josh Charnley made the difference for Wigan, while Leeds have doubts over Kallum Watkins and Lee Smith for the World Club Challenge against Manly on Friday.
Hull had a long and fruitless trip to the South of France, only for their game at the Catalan Dragons to fall foul of the weather and be postponed because of a frozen pitch.
St Helens inaugurated their new ground, Langtree Park, with a 38-10 win over Salford on Friday night. Although they trailed at half-time, Saints cut loose with six tries in the last half-hour to secure the win.