Greg Norman and Sir Nick Faldo, first and second in the record-breaking 1993 Open at Sandwich, will not be involved in this year's championship at the Kent course.
The 56-year-old Australian underwent further shoulder surgery in February and, like Faldo, has not filed an entry for the event on 14-17 July. Norman's 267 total 28 years ago remains the lowest score in Open history and he is also the only man to have won the title with a closing 64 – his last major victory.
Just three years ago he was leading with nine to play at Royal Birkdale before slipping to third.
Norman did not play at St Andrews last July following a right shoulder operation the previous September, but his latest surgery was on his left shoulder – the same one that was operated on in 1998.
Faldo finished second, two strokes behind Norman in 1993 and in the second round equalled the major record with a 63, but he has not played a tournament since missing the cut at St Andrews last July.