Hull, with one point from five matches, introduce Maea David and Tevita Vaikona in the centres and Shane Endacott at stand-off. 'They will strengthen us in positions where we have been weak,' Tony Gordon, Hull's former New Zealand Test coach, said. 'In some matches, our wingers haven't seen the ball at all.'
Oldham, who gained their first points last week, by beating Doncaster, have Mike Kuiti, Chris Parr and Ian Sherratt all doubtful.
Doncaster will be without their South African full-back, Jamie Bloem, at home to Warrington. Bloem was sent off for a high, off-the-ball tackle on Kuiti and has been suspended for three matches.
Warrington will be without Jonathan Davies, who has a hamstring strain. Their coach, Brian Johnson, has also dropped Dave Elliott and Kevin Ellis, with Francis Maloney making his debut after his summer transfer from Featherstone.
Salford give Andy Gregory his first start of the season and he forms a new, but vastly experienced half-back partnership with another former Wigan player, Sam Panapa, for the visit of Halifax.