The Scotland wing Kenny Logan supplied 17 of Wasps' points with a try, three conversions and two penalties. Their other two tries came from the England captain Lawrence Dallaglio and Paul Sampson while Barrie-Jon Mather and Matt Moore went over for Sale.
Relegated West Hartlepool's gloom deepened as they went down 26-14 away to London Scottish. The Zimbabwean wing Conan Sharman ran in both the Exiles' touchdowns and the South African fly-half Jannie de Beer kicked 16 points.
In Premiership Two, Adam Smallwood helped himself to four tries as Coventry swept aside Wakefield 40-13. Simon Verbickas claimed a hat-trick in Orrell's 59-15 trouncing of neighbours Waterloo, but Fylde finished bottom after losing 25-11 to London Welsh.
The Tetley's Bitter County Championship final at Twickenham on 22 May will match Cornwall, who beat Cheshire 35-16 at Redruth, with Gloucestershire, who needed extra time before eclipsing Lancashire 23-20 at Vale of Lune.
Newcastle's reserves succumbed predictably to a 70-20 drubbing in their Anglo-Welsh Friendly at Cardiff, whose wings Jamie Robinson and Simon Hill shared seven tries.
Llanelli saw off Pontypridd 41-22 in the Welsh Premier Division play- offs. Bridgend stole a 37-33 win off Aberavon when their lock Steve Ford drove over for his second try in injury time, and Brett Davey contributed 16 points as Caerphilly saw off Newport 36-22.
Stormers and Queensland secured semi-final berths in the Super 12 with victories overWaikato and Cats respectively. Bulls finally won at the 10th attempt with a 21-19 success over Auckland, and Canterbury strengthened their grip on a place in the last four by spearing the Sharks 34-29.