Jonathan Sexton has been ruled out of Leinster's Heineken Cup semi-final against Toulouse tomorrow.
Sexton has conceded defeat in his battle to recover from the fractured jaw he sustained in the last-eight victory over Clermont three weeks ago.
Leinster coach Michael Cheika has confirmed the Ireland fly-half will be replaced by Shaun Berne.
"Jonny was desperate to play and we gave him every opportunity," said Cheika.
"But we felt it was too big a risk and we also have the player's welfare and safety in mind.
"We have 100% confidence that Shaun Berne can do the job."