England will start with five uncapped players in Sunday's non-cap international against the Barbarians at Twickenham.
Harlequins prop Joe Marler, Worcester lock Graham Kitchener, Exeter flanker Tom Johnson and Sale loose-forward Carl Fearns all feature in the pack while Gloucester's Henry Trinder has been named at outside centre.
Gloucester number eight Luke Narraway, confirmed as captain earlier this week, is among a group of more experienced players looking to press their claims for a place in England's World Cup training squad.
Prop Paul Doran-Jones and lock Dave Attwood are both live World Cup contenders while England are using this game as an opportunity to try Matt Banahan at inside centre.
Charlie Hodgson, who like Banahan seems set for a place in England's full World Cup squad, starts at fly-half with Paul Hodgson at scrum-half.
Ugo Monye and James Simpson-Daniel start on the wings and Mike Brown gets a run at full-back after an impressive season for Harlequins.
The bulk of the squad, being coached by Stuart Lancaster, will remain together for next month's Churchill Cup.
Lancaster said: "It's a very exciting line-up with a good blend of experience and youth and we have the opportunity to measure ourselves against a very experienced Barbarians side including some of the very best players in the world on Sunday.
"It is a young England side and the match day squad has an average age of 23, but these are players who've been in terrific form for their clubs and many of them have played a major part in big games at the end of the season in the Aviva Premiership and in Europe."
England team to play the Barbarians in Sunday's non-cap international at Twickenham (kick-off 2.30pm):
M Brown (Harlequins), J Simpson-Daniel (Gloucester), H Trinder (Gloucester), M Banahan (Bath), U Monye (Harlequins), C Hodgson (Sale), P Hodgson (London Irish); J Marler (Harlequins), D Paice (London Irish), P Doran-Jones (Gloucester), G Kitchener (Worcester), D Attwood (Gloucester), T Johnson (Exeter), C Fearns (Sale), L Narraway (Gloucester, capt)
Replacements: J Gray (Harlequins), K Brookes (Newcastle), J Gaskell (Sale), J Gibson (London Irish), M Young (Newcastle), S Myler (Northampton), J Turner-Hall (Harlequins).